Gα t1 Antibody (F-7): sc-518145
- Gα t1 Antibody (F-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 112-131 of Gα t1 of mouse origin
- recommended for detection of Gα t1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Gα t1 Antibody (F-7) for WB applications. These reagents are now offered in bundles with Gα t1 Antibody (F-7) (see ordering information below).
Gα t1 Antibody (F-7) is a mouse monoclonal IgG2a antibody that detects Gα t1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Gα t1 is a crucial member of the G protein family, specifically involved in the visual signaling pathway, where Gα t1 plays a vital role in the transduction of light signals in photoreceptor cells. Located in the photoreceptor cells of the retina, Gα t1 interacts with photorhodopsin, facilitating the exchange of guanine nucleotides and ultimately leading to the activation of downstream signaling cascades that result in visual perception. The proper functioning of Gα t1 is essential for normal vision, as any dysfunction can lead to visual impairments or disorders. Anti-Gα t1 antibody (F-7) provides reliable detection and characterization of this important protein, making anti-Gα t1 antibody (F-7) an invaluable tool for researchers studying visual signal transduction and related pathways.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Gα t1 Antibody (F-7) References:
- Diffusion and light-dependent compartmentalization of transducin. | Kerov, V. and Artemyev, NO. 2011. Mol Cell Neurosci. 46: 340-6. PMID: 21044685
- A novel homozygous truncating GNAT1 mutation implicated in retinal degeneration. | Carrigan, M., et al. 2016. Br J Ophthalmol. 100: 495-500. PMID: 26472407
- A novel long non-coding RNA lnc-GNAT1-1 is low expressed in colorectal cancer and acts as a tumor suppressor through regulating RKIP-NF-κB-Snail circuit. | Ye, C., et al. 2016. J Exp Clin Cancer Res. 35: 187. PMID: 27912775
- Identification of a Novel Homozygous Nonsense Mutation Confirms the Implication of GNAT1 in Rod-Cone Dystrophy. | Méjécase, C., et al. 2016. PLoS One. 11: e0168271. PMID: 27977773
- Long non‑coding RNA lnc‑GNAT1‑1 inhibits gastric cancer cell proliferation and invasion through the Wnt/β‑catenin pathway in Helicobacter pylori infection. | Liu, L., et al. 2018. Mol Med Rep. 18: 4009-4015. PMID: 30132541
- Coexistence of GNAT1 and ABCA4 variants associated with Nougaret-type congenital stationary night blindness and childhood-onset cone-rod dystrophy. | Hayashi, T., et al. 2020. Doc Ophthalmol. 140: 147-157. PMID: 31583501
- Transducin Partners Outside the Phototransduction Pathway. | Srivastava, D., et al. 2020. Front Cell Neurosci. 14: 589494. PMID: 33173469
- Long Non-coding RNA lnc-GNAT1-1 Suppresses Liver Cancer Progression via Modulation of Epithelial-Mesenchymal Transition. | Wang, J., et al. 2020. Front Genet. 11: 1029. PMID: 33193591
- Sleep Deprivation Does not Change the Flash Electroretinogram in Wild-type and Opn4-/-Gnat1-/- Mice. | Schoonderwoerd, RA., et al. 2022. J Biol Rhythms. 37: 216-221. PMID: 35132885
- Robust visual cortex evoked potentials (VEP) in Gnat1 and Gnat2 knockout mice. | Flood, MD., et al. 2022. Front Cell Neurosci. 16: 1090037. PMID: 36605613
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Gα t1 Antibody (F-7) | sc-518145 | 200 µg/ml | $322.00 | |||
Gα t1 Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-538850 | 200 µg Ab; 10 µg BP | $361.00 | |||
Gα t1 Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-536534 | 200 µg Ab; 40 µg BP | $361.00 | |||
Gα t1 Antibody (F-7): m-IgG2a BP-HRP Bundle | sc-548428 | 200 µg Ab; 10 µg BP | $361.00 |