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GALK1 Antibody (F-3) is a mouse monoclonal IgG2b antibody that detects galactose kinase (GALK1) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GALK1 plays a pivotal role in galactose metabolism, catalyzing the phosphorylation of galactose to galactose-1-phosphate, which is essential for proper sugar utilization in energy production and biosynthesis. GALK1 function extends beyond metabolism; defects in GALK1 can lead to galactosemia II, a serious autosomal recessive disorder that manifests in infancy with congenital cataracts, often appearing within the first two weeks of life. In adults, galactitol accumulation due to impaired GALK1 function can result in presenile cataracts, highlighting GALK1′s critical role in maintaining ocular health. Anti-GALK1 antibody (F-3) serves as an invaluable tool for researchers studying galactose metabolism and associated disorders, providing insights into underlying molecular mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GALK1 Antibody (F-3) | sc-398476 | 200 µg/ml | $322.00 | |||
GALK1 Antibody (F-3): m-IgGκ BP-HRP Bundle | sc-536069 | 200 µg Ab; 40 µg BP | $361.00 | |||
GALK1 Antibody (F-3): m-IgG2b BP-HRP Bundle | sc-549510 | 200 µg Ab; 10 µg BP | $361.00 |