galectin-1 Antibody (E-2): sc-166619

Galectin-1 Antibody (E-2) is a mouse monoclonal IgG2b antibody that detects galectin-1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Galectin-1, also known as LGALS1, is a critical protein that plays a significant role in regulating cell proliferation, particularly in maintaining the G0 phase and controlling the transition through G2, which is essential for proper cell cycle progression. Anti-galectin-1 antibody (E-2) recognizes a protein encoded by a single gene located on human chromosome 22q13.1 and consists of 135 amino acids, featuring a single internal EcoRI site and a polyadenylation signal. Galectin-1 localizes in both intracellular and extracellular environments, which is vital for modulating cell-to-cell adhesion and interactions with the extracellular matrix. Expression of galectin-1 is observed in various human tissues and cell lines, including the placenta, lung, HL-6, HepG2, and CEM cells, highlighting its importance in diverse biological processes and potential implications in tumor progression and apoptosis. Galectin-1 (E-2) antibody provides a reliable tool for researchers investigating the multifaceted roles of galectin-1 in cellular functions and disease mechanisms.

The preferred galectin-1 antibody is galectin-1 Antibody (C-8): sc-166618.