Galanin Antibody (B-8): sc-166927
- Galanin Antibody (B-8) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 104-123 near the C-terminus of Galanin of human origin
- recommended for detection of Galanin precursor and Galanin message-associated peptide (GMAP) of human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP is the preferred secondary detection reagent for Galanin Antibody (B-8) for WB applications. This reagent is now offered in a bundle with Galanin Antibody (B-8) (see ordering information below).
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Galanin Antibody (B-8) is a mouse monoclonal IgG2b antibody that detects Galanin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Galanin is a neuropeptide that plays a crucial role in various physiological functions, including the regulation of reproduction and the modulation of neurotransmission and memory processes. Galanin is primarily located in the central nervous system, particularly within brain regions associated with cognition and emotional regulation, which underscores its importance in both behavioral and physiological responses. Galanin in these areas suggests influence on learning and memory by modulating neurotransmitter release and neuronal firing rates, thereby impacting synaptic plasticity. Additionally, Galanin has been shown to interact with specific receptors and signaling pathways that further elucidate its role in neuroendocrine functions and stress responses. Anti-Galanin antibody (B-8) is an essential tool for researchers aiming to explore the multifaceted roles of this neuropeptide in human health and disease.
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Galanin Antibody (B-8) References:
- Galanin/GALP receptors and CNS homeostatic processes. | Robinson, JK., et al. 2006. CNS Neurol Disord Drug Targets. 5: 327-34. PMID: 16787232
- Galanin acts as a trophic factor to the central and peripheral nervous systems. | Hobson, SA., et al. 2010. Exp Suppl. 102: 25-38. PMID: 21299059
- Crosstalk between exercise and galanin system alleviates insulin resistance. | Fang, P., et al. 2015. Neurosci Biobehav Rev. 59: 141-6. PMID: 26542124
- Type 2 diabetes mellitus as a disorder of galanin resistance. | Fang, P., et al. 2016. Exp Gerontol. 73: 72-7. PMID: 26585047
- Regulatory effects of galanin system on development of several age-related chronic diseases. | Fang, P., et al. 2017. Exp Gerontol. 95: 88-97. PMID: 28450241
- Galanin suppresses proliferation of human U251 and T98G glioma cells via its subtype 1 receptor. | Mei, Z., et al. 2017. Biol Chem. 398: 1127-1139. PMID: 28525358
- The galanin and galanin receptor subtypes, its regulatory role in the biological and pathological functions. | Šípková, J., et al. 2017. Physiol Res. 66: 729-740. PMID: 28730831
- Beneficial effects of galanin system on diabetic peripheral neuropathic pain and its complications. | Yu, M., et al. 2020. Peptides. 134: 170404. PMID: 32898581
- Serum Galanin in Children with Autism Spectrum Disorder. | Saad, K., et al. 2022. Child Psychiatry Hum Dev. 53: 300-306. PMID: 33534034
- The neuropeptide galanin adopts an irregular secondary structure. | Wilkinson, RE., et al. 2022. Biochem Biophys Res Commun. 626: 121-128. PMID: 35994823
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Galanin Antibody (B-8) | sc-166927 | 200 µg/ml | $316.00 | |||
Galanin Antibody (B-8): m-IgG2b BP-HRP Bundle | sc-548534 | 200 µg Ab; 10 µg BP | $354.00 | |||
Galanin (B-8) Neutralizing Peptide | sc-166927 P | 100 µg/0.5 ml | $68.00 |