GAIP Antibody (A-10): sc-365157
- GAIP Antibody (A-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 189-216 at the C-terminus of GAIP of human origin
- recommended for detection of GAIP of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for GAIP Antibody (A-10) for WB applications. These reagents are now offered in bundles with GAIP Antibody (A-10) (see ordering information below).
QUICK LINKS
SEE ALSO...
GAIP Antibody (A-10) is a mouse monoclonal IgG1 antibody that detects GAIP in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). GAIP, or Gα-interacting protein, plays a crucial role in the regulation of G protein signaling pathways by acting as a GTPase-activating protein (GAP) for specific Gα subunits, particularly Gα i, Gα o, and Gα t. This regulation is vital for maintaining cellular homeostasis and ensuring proper signal transduction, as GAIP accelerates the conversion of GTP to GDP, effectively turning off the signaling cascade initiated by G protein-coupled receptors. GAIP′s ability to selectively deactivate these Gα isoforms underscores its importance in modulating various physiological processes, including neurotransmission and immune responses. Additionally, GAIP′s interactions with other proteins, such as RGS1, RGS4, and RGS10, further illustrate GAIP′s integral role in the complex network of G protein signaling, making anti-GAIP antibody (A-10) an essential tool for researchers studying these pathways and their implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
GAIP Antibody (A-10) | sc-365157 | 200 µg/ml | $322.00 | |||
GAIP Antibody (A-10): m-IgG Fc BP-HRP Bundle | sc-537781 | 200 µg Ab; 10 µg BP | $361.00 | |||
GAIP Antibody (A-10): m-IgGκ BP-HRP Bundle | sc-535164 | 200 µg Ab; 40 µg BP | $361.00 | |||
GAIP Antibody (A-10): m-IgG1 BP-HRP Bundle | sc-545348 | 200 µg Ab; 20 µg BP | $361.00 | |||
GAIP (A-10) Neutralizing Peptide | sc-365157 P | 100 µg/0.5 ml | $69.00 |