FTα Antibody (B-1): sc-390757
- FTα Antibody (B-1) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 353-377 of FTα of rat origin
- recommended for detection of FTα of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FTα Antibody (B-1) for WB applications. These reagents are now offered in bundles with FTα Antibody (B-1) (see ordering information below).
FTα Antibody (B-1) is a mouse monoclonal IgG2a antibody that detects FTα in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FTα, or farnesyl transferase alpha, plays a crucial role in the post-translational modification of proteins by catalyzing the attachment of farnesyl groups to specific cysteine residues, which is essential for the proper localization and function of various signaling proteins, including p21Ras. The farnesylation process is vital for the membrane association of these proteins, influencing their activity and interactions within cellular pathways that regulate growth and differentiation. Aberrations in farnesyl transferase activity can lead to various diseases, including cancer, making FTα a significant target for therapeutic intervention. Anti-FTα antibody (B-1) is particularly valuable for researchers studying the dynamics of protein farnesylation and its implications in cellular signaling and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FTα Antibody (B-1) | sc-390757 | 200 µg/ml | $322.00 | |||
FTα Antibody (B-1): m-IgG Fc BP-HRP Bundle | sc-538099 | 200 µg Ab; 10 µg BP | $361.00 | |||
FTα Antibody (B-1): m-IgGκ BP-HRP Bundle | sc-535642 | 200 µg Ab; 40 µg BP | $361.00 | |||
FTα (B-1) Neutralizing Peptide | sc-390757 P | 100 µg/0.5 ml | $69.00 |