FOXM1 Antibody (G-5): sc-376471
- FOXM1 Antibody (G-5) is a mouse monoclonal IgG2b κ FOXM1 antibody, cited in 64 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 734-763 at the C-terminus of FOXM1 of human origin
- FOXM1 Antibody (G-5) is recommended for detection of all isoforms of FOXM1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-FOXM1 Antibody (G-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-376471 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FOXM1 Antibody (G-5) for WB and IHC(P) applications. These reagents are now offered in bundles with FOXM1 Antibody (G-5) (see ordering information below).
FOXM1 Antibody (G-5) is a mouse monoclonal IgG2b kappa light chain antibody engineered to detect FOXM1 across mouse, rat, and human species through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). FOXM1 monoclonal antibody (G-5) targets a precise epitope mapping between amino acids 734-763 at the C-terminus of human FOXM1, ensuring robust and reliable binding for accurate detection and analysis. Forkhead box M1 (FOXM1), also called FKHL16, HFH11, INS-1, and PIG29, is a pivotal transcription factor characterized by its distinct forkhead or winged-helix DNA-binding domain, which facilitates the regulation of genes essential for cell cycle progression, particularly during the transition from G1 to S phase and mitosis. The structural integrity of FOXM1, including its C-terminal region where the G-5 epitope is located, is crucial for DNA interaction and regulatory protein binding, thereby influencing processes such as cellular proliferation, differentiation, and DNA repair. Proper structural conformation of FOXM1 ensures normal cell growth and tissue regeneration, while alterations in structure can lead to uncontrolled cell division and tumorigenesis, making FOXM1 a significant target in cancer research. Additionally, FOXM1 undergoes alternative splicing to produce isoforms like FOXM1A and FOXM1B, which possess distinct structural features affecting stability and function, further highlighting the importance of structural domains in regulatory capabilities. Anti-FOXM1 antibody (G-5) is available in both non-conjugated form and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for diverse experimental needs. FOXM1 (G-5) antibody enables researchers to effectively investigate structural and functional dynamics in both normal physiological and pathological states, thereby advancing the understanding of FOXM1′s role in diseases such as cancer and facilitating targeted therapeutic strategy development.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FOXM1 Antibody (G-5) | sc-376471 | 200 µg/ml | $322.00 | |||
FOXM1 Antibody (G-5): m-IgG Fc BP-HRP Bundle | sc-529873 | 200 µg Ab; 10 µg BP | $361.00 | |||
FOXM1 Antibody (G-5): m-IgGκ BP-HRP Bundle | sc-522963 | 200 µg Ab, 40 µg BP | $361.00 | |||
FOXM1 Antibody (G-5): m-IgG2b BP-HRP Bundle | sc-550146 | 200 µg Ab; 10 µg BP | $361.00 | |||
FOXM1 Antibody (G-5) X | sc-376471 X | 200 µg/0.1 ml | $322.00 | |||
FOXM1 Antibody (G-5) AC | sc-376471 AC | 500 µg/ml, 25% agarose | $424.00 | |||
FOXM1 Antibody (G-5) HRP | sc-376471 HRP | 200 µg/ml | $322.00 | |||
FOXM1 Antibody (G-5) FITC | sc-376471 FITC | 200 µg/ml | $336.00 | |||
FOXM1 Antibody (G-5) PE | sc-376471 PE | 200 µg/ml | $349.00 | |||
FOXM1 Antibody (G-5) Alexa Fluor® 488 | sc-376471 AF488 | 200 µg/ml | $364.00 | |||
FOXM1 Antibody (G-5) Alexa Fluor® 546 | sc-376471 AF546 | 200 µg/ml | $364.00 | |||
FOXM1 Antibody (G-5) Alexa Fluor® 594 | sc-376471 AF594 | 200 µg/ml | $364.00 | |||
FOXM1 Antibody (G-5) Alexa Fluor® 647 | sc-376471 AF647 | 200 µg/ml | $364.00 | |||
FOXM1 Antibody (G-5) Alexa Fluor® 680 | sc-376471 AF680 | 200 µg/ml | $364.00 | |||
FOXM1 Antibody (G-5) Alexa Fluor® 790 | sc-376471 AF790 | 200 µg/ml | $364.00 | |||
FOXM1 (G-5) Neutralizing Peptide | sc-376471 P | 100 µg/0.5 ml | $69.00 |