FNDC3B Antibody (B-6): sc-393875
- FNDC3B Antibody (B-6) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 1-42 mapping at the N-terminus of FNDC3B of human origin
- recommended for detection of FNDC3B of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FNDC3B Antibody (B-6) for WB applications. These reagents are now offered in bundles with FNDC3B Antibody (B-6) (see ordering information below).
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FNDC3B Antibody (B-6) is a mouse monoclonal IgG2b kappa light chain antibody that detects FNDC3B protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-FNDC3B antibody (B-6) plays a significant role in studying adipogenesis, the process by which pre-adipocytes differentiate into mature adipocytes, which is crucial for understanding obesity and type II diabetes. FNDC3B protein, also known as factor for adipocyte differentiation 104 or HCV NS5A-binding protein 37, is expressed during early stages of adipogenesis and is essential for proper functioning of adipocytes. These cells are not only responsible for storing energy but also secrete various hormones and bioactive peptides that influence numerous physiological processes, including hemostasis, angiogenesis, and energy balance. FNDC3B protein is a 1,204 amino acid molecule characterized by nine fibronectin type-III domains, which are important for structural integrity and function. Notably, FNDC3B-deficient mice exhibit a lethal phenotype within one day of birth, underscoring FNDC3B′s critical role in survival and development. Furthermore, studies have shown that mouse embryonic fibroblasts lacking FNDC3B function demonstrate impaired stress fiber formation, indicating FNDC3B′s vital role in cellular processes such as proliferation, adhesion, spreading, and migration. FNDC3B monoclonal antibody (B-6) serves as an invaluable tool for researchers investigating mechanisms of adipocyte differentiation and related metabolic disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FNDC3B Antibody (B-6) | sc-393875 | 200 µg/ml | $322.00 | |||
FNDC3B Antibody (B-6): m-IgGκ BP-HRP Bundle | sc-535915 | 200 µg Ab; 40 µg BP | $361.00 | |||
FNDC3B Antibody (B-6): m-IgG2b BP-HRP Bundle | sc-549488 | 200 µg Ab; 10 µg BP | $361.00 |