FMO3 Antibody (D-9): sc-514882

FMO3 Antibody (D-9) is a mouse monoclonal IgG1 antibody that detects FMO3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FMO3, a member of the flavin-containing monooxygenase family, plays a crucial role in the metabolism of various xenobiotics and therapeutics, primarily functioning as a hepatic microsomal enzyme located in the liver. This enzyme is essential for the N-oxygenation of soft nucleophiles, including secondary and tertiary amines, which facilitates the oxidative digestion of a wide range of compounds. Notably, defects in the FMO3 gene can lead to trimethylaminuria, a metabolic disorder characterized by the production of a fishy odor in sweat, urine, and breath due to the accumulation of trimethylamine. Genetic mutations in FMO3 disrupt the normal N-oxidation process, resulting in the malodor associated with this condition. FMO3 (D-9) antibody is invaluable for researchers studying the metabolic pathways involving FMO3 and its implications in human health, particularly in understanding the genetic factors contributing to trimethylaminuria and other metabolic disorders.

The preferred FMO3 antibody is FMO3 Antibody (C-1): sc-515042.