Fibulin-1 Antibody (A-5): sc-55470
- Fibulin-1 Antibody (A-5) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 1-190 of Fibulin-1 of human origin
- recommended for detection of Fibulin-1 of human origin by WB, IP, IF, IHC(P) and ELISA
- See Fibulin-1 (B-5): sc-25281 for Fibulin-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Fibulin-1 Antibody (A-5) for WB and IHC(P) applications. These reagents are now offered in bundles with Fibulin-1 Antibody (A-5) (see ordering information below).
Fibulin-1 Antibody (A-5) is a mouse monoclonal IgG2a antibody that detects Fibulin-1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Fibulin-1 is a crucial modular glycoprotein that plays a significant role in the structure and function of the extracellular matrix, particularly in elastic fibers, basement membranes, and blood. The unique structure of Fibulin-1, characterized by multiple epidermal growth factor (EGF)-like domains and fibulin-type modules, allows interactions with various extracellular matrix components such as calcium, fibronectin, laminin, nidogen, and fibrinogen. These interactions are vital for maintaining tissue integrity and facilitating cellular communication within the extracellular matrix. Notably, Fibulin-1′s ability to self-associate and bind to other proteins suggests involvement in the assembly and stabilization of the extracellular matrix, which is essential for proper tissue function and repair. Furthermore, Fibulin-1 expression is influenced by estrogen in ovarian cancer cell lines, indicating potential roles in cancer progression and metastasis, as well as utility as a biomarker for assessing cancer risk and aggressiveness. The multifaceted nature of Fibulin-1 underscores importance in both normal physiological processes and pathological conditions, making anti-Fibulin-1 antibody (A-5) a valuable tool for researchers studying these dynamics.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibulin-1 Antibody (A-5) | sc-55470 | 200 µg/ml | $316.00 | |||
Fibulin-1 Antibody (A-5): m-IgG Fc BP-HRP Bundle | sc-537041 | 200 µg Ab; 10 µg BP | $354.00 | |||
Fibulin-1 Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-534225 | 200 µg Ab; 40 µg BP | $354.00 |