FGF-1 Antibody (D-11): sc-13123
- FGF-1 Antibody (D-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 16-140 of FGF-1 of human origin
- recommended for detection of precursor and mature FGF-1 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FGF-1 Antibody (D-11) for WB applications. These reagents are now offered in bundles with FGF-1 Antibody (D-11) (see ordering information below).
FGF-1 Antibody (D-11) is a mouse monoclonal IgG2b antibody that detects fibroblast growth factor-1 (FGF-1) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FGF-1 plays a crucial role in various biological processes, including cell proliferation, differentiation, and survival, making FGF-1 essential for tissue repair and development. FGF-1 is primarily located in the extracellular space, where FGF-1 binds to specific fibroblast growth factor receptors (FGFRs) on the cell surface, initiating signaling pathways that promote angiogenesis and wound healing. The interaction between FGF-1 and FGFRs is vital for maintaining normal physiological functions, and dysregulation of this pathway can lead to pathological conditions such as cancer and cardiovascular diseases. FGF-1 (D-11) antibody is an invaluable tool for researchers studying these processes, providing insights into the mechanisms of cell signaling and the potential therapeutic targets for various diseases.
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FGF-1 Antibody (D-11) References:
- A Network Map of FGF-1/FGFR Signaling System. | Raju, R., et al. 2014. J Signal Transduct. 2014: 962962. PMID: 24829797
- Catabolic effects of FGF-1 on chondrocytes and its possible role in osteoarthritis. | El-Seoudi, A., et al. 2017. J Cell Commun Signal. 11: 255-263. PMID: 28343287
- Epigenetic regulation of Fgf1 transcription by CRTC1 and memory enhancement. | Uchida, S. and Shumyatsky, GP. 2018. Brain Res Bull. 141: 3-12. PMID: 29477835
- Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. | Wang, S., et al. 2020. Nat Commun. 11: 2303. PMID: 32385276
- FGF1ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression. | Wang, D., et al. 2021. Signal Transduct Target Ther. 6: 133. PMID: 33762571
- MicroRNA-27b-3p down-regulates FGF1 and aggravates pathological cardiac remodelling. | Li, G., et al. 2022. Cardiovasc Res. 118: 2139-2151. PMID: 34358309
- FGF1 and insulin control lipolysis by convergent pathways. | Sancar, G., et al. 2022. Cell Metab. 34: 171-183.e6. PMID: 34986332
- FGF1 alleviates LPS-induced acute lung injury via suppression of inflammation and oxidative stress. | Dhlamini, Q., et al. 2022. Mol Med. 28: 73. PMID: 35764933
- Exogenous FGF-1 Differently Regulates Oligodendrocyte Replenishment in an SCI Repair Model and Cultured Cells. | Lee, MJ., et al. 2022. Biomedicines. 10: PMID: 36359244
- Platelet deposition on ePTFE grafts coated with fibrin glue with or without FGF-1 and heparin. | Zarge, JI., et al. 1997. J Surg Res. 67: 4-8. PMID: 9070173
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FGF-1 Antibody (D-11) | sc-13123 | 200 µg/ml | $316.00 | |||
FGF-1 Antibody (D-11): m-IgG Fc BP-HRP Bundle | sc-536573 | 200 µg Ab; 10 µg BP | $354.00 | |||
FGF-1 Antibody (D-11): m-IgGκ BP-HRP Bundle | sc-533724 | 200 µg Ab; 40 µg BP | $354.00 | |||
FGF-1 Antibody (D-11): m-IgG2b BP-HRP Bundle | sc-549813 | 200 µg Ab; 10 µg BP | $354.00 |