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Ero1-Lα Antibody (D-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ero1-L alpha protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Ero1-Lα (D-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Ero1-La, also known as endoplasmic oxidoreductin-1-like or ERO1A, plays a critical role in oxidative protein folding within the endoplasmic reticulum, essential for proper protein maturation and function. Ero1-La facilitates disulfide bond formation, a key post-translational modification that stabilizes protein structures, by working with protein disulfide isomerase (PDI). Ero1-La and PDI interaction enables efficient folding of immunoglobulins, crucial for immune response. Hypoxia regulates Ero1-La through the hypoxia-inducible transcription factor pathway, indicating significance in cellular responses to low oxygen levels. While most tissues express low levels of Ero1-La, significantly higher expression occurs in the upper digestive tract and esophagus, suggesting a specialized role in these regions. Ero1-La functions as both a monomer and homodimer, highlighting versatility in cellular processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ero1-Lα Antibody (D-7) | sc-365526 | 200 µg/ml | $316.00 | |||
Ero1-Lα Antibody (D-7): m-IgG Fc BP-HRP Bundle | sc-529388 | 200 µg Ab; 10 µg BP | $354.00 | |||
Ero1-Lα Antibody (D-7): m-IgGκ BP-HRP Bundle | sc-522265 | 200 µg Ab, 40 µg BP | $354.00 | |||
Ero1-Lα Antibody (D-7): m-IgG1 BP-HRP Bundle | sc-543494 | 200 µg Ab; 20 µg BP | $354.00 | |||
Ero1-Lα Antibody (D-7) AC | sc-365526 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Ero1-Lα Antibody (D-7) HRP | sc-365526 HRP | 200 µg/ml | $316.00 | |||
Ero1-Lα Antibody (D-7) FITC | sc-365526 FITC | 200 µg/ml | $330.00 | |||
Ero1-Lα Antibody (D-7) PE | sc-365526 PE | 200 µg/ml | $343.00 | |||
Ero1-Lα Antibody (D-7) Alexa Fluor® 488 | sc-365526 AF488 | 200 µg/ml | $357.00 | |||
Ero1-Lα Antibody (D-7) Alexa Fluor® 546 | sc-365526 AF546 | 200 µg/ml | $357.00 | |||
Ero1-Lα Antibody (D-7) Alexa Fluor® 594 | sc-365526 AF594 | 200 µg/ml | $357.00 | |||
Ero1-Lα Antibody (D-7) Alexa Fluor® 647 | sc-365526 AF647 | 200 µg/ml | $357.00 | |||
Ero1-Lα Antibody (D-7) Alexa Fluor® 680 | sc-365526 AF680 | 200 µg/ml | $357.00 | |||
Ero1-Lα Antibody (D-7) Alexa Fluor® 790 | sc-365526 AF790 | 200 µg/ml | $357.00 |