Estrogen Receptor beta Antibody (1531): sc-53494

ERβ Antibody (1531) is a mouse monoclonal IgG2a kappa light chain antibody that detects Estrogen Receptor beta (ERβ) of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). ERβ (1531) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Estrogen Receptor beta plays a crucial role in mediating estrogen effects, particularly in regulating gene expression related to reproductive tissues and other physiological processes. Located primarily in the nucleus, Estrogen Receptor beta can also associate with the cell membrane, allowing rapid activation upon estrogen exposure. This unique localization enables Estrogen Receptor beta to participate in both genomic and non-genomic signaling pathways, influencing cellular responses to hormonal changes. Estrogen Receptor beta′s ability to dimerize and interact with specific regulatory elements in target genes is essential for function, and research has shown differential activation by various ligands, leading to distinct biological outcomes. Understanding Estrogen Receptor beta dynamics and interactions is vital for elucidating roles in health and disease, particularly in conditions influenced by estrogen signaling.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Estrogen Receptor beta Antibody (1531) has 67 citations in a variety of scientific publications.

Primary antibodies like Anti-Estrogen Receptor beta Antibody (1531) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Estrogen Receptor beta Antibody (1531) Specifications

Alternate Product Name: Estrogen Receptor beta

Product Clone Name: 1531

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a kappa light chain

Amino Acids: 256-505

Epitope Target: ERβ

Epitope Species: human

Product Reactivity/Detection: ERβ

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF

Vialing Information: Each vial contains 200 µg IgG_2a kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 67 citations in various scientific publications

Available Conjugates/Forms for Estrogen Receptor beta Antibody (1531): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Estrogen Receptor beta antibody is Estrogen Receptor beta Antibody (B-1): sc-390243.