ER beta Activators
SEE ALSO...
Items 1 to 10 of 19 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Tamoxifen functions as a selective estrogen receptor beta (ERβ) modulator, exhibiting unique binding affinities that promote distinct conformational states of the receptor. Its molecular structure enables specific electrostatic interactions and hydrophobic contacts, which stabilize the receptor-ligand complex. This compound influences downstream signaling pathways by altering the recruitment of co-factors, thereby modulating gene transcription and cellular responses in a nuanced manner. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
Directly binds to and activates ERβ, triggering estrogen-responsive gene transcription. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Phytoestrogen that can selectively activate ERβ over ERα. | ||||||
ERB 041 | 524684-52-4 | sc-362734 sc-362734A | 10 mg 50 mg | $219.00 $877.00 | ||
ERB 041 acts as a selective modulator of the estrogen receptor beta, showcasing a unique ability to induce specific allosteric changes in the receptor's conformation. Its molecular design facilitates targeted interactions with key amino acid residues, enhancing receptor stability and selectivity. This compound can influence the dynamics of protein-protein interactions, thereby affecting the transcriptional activity of various genes and altering cellular signaling cascades in a precise manner. | ||||||
DPN | 1428-67-7 | sc-203431 sc-203431A | 10 mg 50 mg | $100.00 $423.00 | 4 | |
DPN is a selective modulator of estrogen receptor beta, characterized by its unique ability to stabilize receptor conformations through specific hydrophobic interactions. Its molecular structure facilitates distinct binding kinetics, allowing for a rapid onset of action. DPN's interactions can lead to differential activation of transcriptional responses, influencing cellular signaling cascades. This compound's selectivity for ER beta over ER alpha highlights its potential for targeted modulation of estrogenic activity. | ||||||
(R,S)-Equol | 94105-90-5 | sc-202307 sc-202307A | 5 mg 25 mg | $32.00 $142.00 | 2 | |
(R,S)-Equol is a chiral compound that selectively binds to estrogen receptor beta, exhibiting unique stereochemical properties that influence its interaction dynamics. Its dual enantiomeric forms allow for differential binding affinities, which can modulate receptor activity through distinct conformational shifts. This compound also engages in specific hydrogen bonding and hydrophobic interactions with the receptor, potentially altering downstream signaling pathways and gene expression profiles in a nuanced manner. | ||||||
(R)-Equol | 221054-79-1 | sc-222235 sc-222235A | 1 mg 5 mg | $27.00 $120.00 | 2 | |
(R)-Equol is a chiral compound that selectively binds to estrogen receptor beta, exhibiting unique stereochemical properties that enhance its affinity for the receptor. Its binding induces conformational changes that promote specific downstream signaling pathways, influencing gene expression. The compound's ability to form hydrogen bonds and engage in hydrophobic interactions contributes to its distinct pharmacodynamics, allowing for nuanced modulation of estrogenic effects in various biological contexts. | ||||||
Daidzein | 486-66-8 | sc-24001 sc-24001A sc-24001B | 100 mg 500 mg 5 g | $25.00 $75.00 $150.00 | 32 | |
Another phytoestrogen that can preferentially activate ERβ. | ||||||
WAY 200070 | 440122-66-7 | sc-301977 sc-301977A | 10 mg 50 mg | $83.00 $435.00 | ||
WAY 200070 is a selective modulator of estrogen receptor beta, characterized by its unique molecular interactions that stabilize receptor conformation. Its structure facilitates specific hydrogen bonding and hydrophobic interactions, enhancing receptor affinity and selectivity. This compound engages distinct signaling pathways, leading to differential gene regulation. The kinetic profile of WAY 200070 suggests a rapid onset of action, with potential for nuanced effects on cellular responses through its receptor interactions. | ||||||
LY500307 | 533884-09-2 | sc-364530 sc-364530A sc-364530B sc-364530C | 5 mg 25 mg 100 mg 200 mg | $600.00 $1600.00 $6000.00 $11223.00 | ||
LY500307 is a selective estrogen receptor beta modulator that exhibits unique binding dynamics, promoting a distinct conformational change in the receptor. Its molecular architecture allows for specific electrostatic interactions, which enhance its selectivity and affinity for ER beta. This compound activates unique downstream signaling cascades, influencing gene expression patterns. The reaction kinetics of LY500307 indicate a prolonged engagement with the receptor, potentially leading to sustained biological effects. | ||||||