ErbB4/HER4 Antibody (3F168): sc-71070
- ErbB4/HER4 Antibody (3F168) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1249-1264 of ErbB-4 of human origin
- recommended for detection of ErbB-4 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See ErbB4/HER4 (C-7): sc-8050 for ErbB4/HER4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ErbB4/HER4 Antibody (3F168). This work is in progress.
ErbB-4 Antibody (3F168) is a mouse monoclonal IgG2b antibody that detects ErbB-4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. ErbB-4 plays a crucial role in cell signaling pathways that regulate cell proliferation and differentiation, making ErbB-4 a significant player in various physiological processes and a potential target in cancer research. ErbB-4 is primarily located in the cell membrane, where ErbB-4 functions as a receptor tyrosine kinase. Upon ligand binding, ErbB-4 can form homodimers or heterodimers with other members of the EGF receptor family, which is essential for initiating downstream signaling cascades that influence cellular responses. ErbB-4 expression is notably high in breast carcinoma cell lines, as well as in normal tissues such as skeletal muscle, heart, pituitary, brain, and cerebellum, highlighting ErbB-4′s importance in both normal physiology and disease states. Anti-ErbB-4 antibody (3F168) recognition of ErbB-4 in various applications makes anti-ErbB-4 antibody (3F168) an invaluable tool for researchers studying ErbB-4′s role in cancer and other conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ErbB4/HER4 Antibody (3F168) | sc-71070 | 200 µg/ml | $322.00 |