eotaxin-2 Antibody (5C38): sc-71053
- eotaxin-2 Antibody (5C38) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against recombinant eotaxin-2 of human origin
- recommended for detection of eotaxin-2 of human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for eotaxin-2 Antibody (5C38). This work is in progress.
eotaxin-2 Antibody (5C38) is a mouse monoclonal IgG1 antibody that detects eotaxin-2 in human samples through western blotting (WB). Eotaxin-2, also known as MPIF-2, CK β-6, or small inducible cytokine A24, plays a crucial role in the immune response by promoting chemotaxis and calcium mobilization in human eosinophils, specifically through CCR3 receptor interaction. This interaction is vital for the recruitment of eosinophils to sites of inflammation, which is important in various allergic and inflammatory conditions. Notably, eotaxin-2 is distinct from other chemokines, such as eotaxin, as eotaxin-2 shares only 39% amino acid homology and exhibits significant differences in the NH2-terminal region, which may influence specific biological functions and receptor interactions. Eotaxin-2′s unique structural features and selective activation of eosinophils underscore eotaxin-2′s importance in understanding the mechanisms of allergic responses and potential therapeutic targets for related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eotaxin-2 Antibody (5C38) | sc-71053 | 100 µg/ml | $322.00 |