eotaxin-2 Antibody (500-M31): sc-57103
- eotaxin-2 Antibody (500-M31) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against recombinant eotaxin-2 of human origin
- recommended for detection of eotaxin-2 of human origin by WB
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for eotaxin-2 Antibody (500-M31). This work is in progress.
eotaxin-2 Antibody (500-M31) is a mouse monoclonal IgG1 antibody that detects eotaxin-2 in human samples through western blotting (WB). Eotaxin-2, also known as MPIF-2, CK β-6, or small inducible cytokine A24, plays a crucial role in the immune response by promoting chemotaxis and calcium mobilization in human eosinophils, specifically through CCR3 receptor interaction. This interaction is vital for recruiting eosinophils to sites of inflammation, which is important in various allergic and inflammatory conditions. Notably, eotaxin-2 is functionally similar to eotaxin but exhibits only 39% amino acid homology, with significant differences in the NH2-terminal region, which may influence specific biological activities and receptor interactions. Eotaxin-2′s unique properties and lack of suppressive activity against immature subsets of myeloid progenitors, even when stimulated by multiple growth factors, highlight a distinct role in immune cell dynamics regulation. Anti-eotaxin-2 antibody (500-M31) is an essential tool for researchers studying eosinophil recruitment mechanisms and broader implications of chemokines in immune responses.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eotaxin-2 Antibody (500-M31) | sc-57103 | 100 µg/ml | $316.00 |