EMMPRIN/CD147 Antibody (B-5): sc-46700

EMMPRIN Antibody (B-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects EMMPRIN in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-EMMPRIN antibody (B-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. EMMPRIN, also known as basigin or CD147, plays a crucial role in regulating matrix remodeling at the epidermal-dermal interface, which is vital for maintaining skin integrity and facilitating wound healing. EMMPRIN is primarily located in the plasma membrane of various cell types, including fibroblasts and endothelial cells, where EMMPRIN interacts with other proteins to modulate matrix metalloproteinases (MMPs) activity. By stimulating the production of interstitial collagenase, gelatinase A, and stromelysin-1, EMMPRIN is instrumental in tissue degradation and repair processes, making EMMPRIN a significant factor in cancer invasion and metastasis. EMMPRIN′s ability to influence the extracellular matrix environment underscores EMMPRIN′s importance in both physiological and pathological contexts, highlighting anti-EMMPRIN antibody (B-5)′s relevance in research and therapeutic applications.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-EMMPRIN/CD147 Antibody (B-5) has 18 citations in a variety of scientific publications.

Primary antibodies like Anti-EMMPRIN/CD147 Antibody (B-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

EMMPRIN/CD147 Antibody (B-5) Specifications

Alternate Product Name: EMMPRIN

Product Clone Name: B-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 1-190

Epitope Target: EMMPRIN

Epitope Species: mouse

Product Reactivity/Detection: EMMPRIN

Species Reactivity/Detection: mouse, rat

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 18 citations in various scientific publications

Available Conjugates/Forms for EMMPRIN/CD147 Antibody (B-5): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred EMMPRIN/CD147 antibody is EMMPRIN/CD147 Antibody (8D6): sc-21746.