ELOVL5 Antibody (B-3): sc-374138
- ELOVL5 Antibody (B-3) is a mouse monoclonal IgG1 κ ELOVL5 antibody, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 211-299 mapping at the C-terminus of ELOVL5 of human origin
- ELOVL5 Antibody (B-3) is recommended for detection of ELOVL5 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ELOVL5 Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ELOVL5 Antibody (B-3) for WB and IHC(P) applications. These reagents are now offered in bundles with ELOVL5 Antibody (B-3) (see ordering information below).
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ELOVL5 Antibody (B-3) is a mouse monoclonal IgG1 kappa light chain antibody that detects ELOVL5 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ELOVL5 (B-3) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The Elongation of Very Long Chain Fatty Acids protein 5 (ELOVL5), also known as HELO1, plays a crucial role in elongating monounsaturated and polyunsaturated fatty acids, specifically those with 18 to 20 carbon chains, which is vital for maintaining cellular membrane integrity and signaling pathways. ELOVL5 is predominantly expressed in the adrenal gland and testis, but is also found in the lung, brain, and prostate tissue, highlighting ELOVL5′s importance in various physiological processes. Additionally, ELOVL5 is localized to the sebaceous glands in the pheromone-producing regions of the skin, suggesting a potential role in pheromone production and regulation, which could have implications for social and reproductive behaviors in humans.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ELOVL5 Antibody (B-3) References:
- Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids. | Leonard, AE., et al. 2000. Biochem J. 350 Pt 3: 765-70. PMID: 10970790
- Identification and expression of a rat fatty acid elongase involved in the biosynthesis of C18 fatty acids. | Inagaki, K., et al. 2002. Biosci Biotechnol Biochem. 66: 613-21. PMID: 12005057
- Identification and expression of mammalian long-chain PUFA elongation enzymes. | Leonard, AE., et al. 2002. Lipids. 37: 733-40. PMID: 12371743
- Depression and adipose polyunsaturated fatty acids in an adolescent group. | Mamalakis, G., et al. 2004. Prostaglandins Leukot Essent Fatty Acids. 71: 289-94. PMID: 15380815
- Mutation screening of three candidate genes, ELOVL5, SMAP1 and GLULD1 in autosomal recessive retinitis pigmentosa. | Barragan, I., et al. 2005. Int J Mol Med. 16: 1163-7. PMID: 16273301
- Fatty acid elongases in mammals: their regulation and roles in metabolism. | Jakobsson, A., et al. 2006. Prog Lipid Res. 45: 237-49. PMID: 16564093
- HNF1alpha inactivation promotes lipogenesis in human hepatocellular adenoma independently of SREBP-1 and carbohydrate-response element-binding protein (ChREBP) activation. | Rebouissou, S., et al. 2007. J Biol Chem. 282: 14437-46. PMID: 17379603
- Differential cerebral cortex transcriptomes of baboon neonates consuming moderate and high docosahexaenoic acid formulas. | Kothapalli, KS., et al. 2007. PLoS One. 2: e370. PMID: 17426818
- Localization of the candidate genes ELOVL5 and SCD1 for 'male effect' pheromone synthesis in goats (Capra hircus). | Kitago, M., et al. 2007. J Reprod Dev. 53: 1329-33. PMID: 17827874
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ELOVL5 Antibody (B-3) | sc-374138 | 200 µg/ml | $316.00 | |||
ELOVL5 Antibody (B-3): m-IgG Fc BP-HRP Bundle | sc-527438 | 200 µg Ab; 10 µg BP | $354.00 | |||
ELOVL5 Antibody (B-3): m-IgG1 BP-HRP Bundle | sc-532811 | 200 µg Ab; 20 µg BP | $354.00 | |||
ELOVL5 Antibody (B-3) AC | sc-374138 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ELOVL5 Antibody (B-3) HRP | sc-374138 HRP | 200 µg/ml | $316.00 | |||
ELOVL5 Antibody (B-3) FITC | sc-374138 FITC | 200 µg/ml | $330.00 | |||
ELOVL5 Antibody (B-3) PE | sc-374138 PE | 200 µg/ml | $343.00 | |||
ELOVL5 Antibody (B-3) Alexa Fluor® 488 | sc-374138 AF488 | 200 µg/ml | $357.00 | |||
ELOVL5 Antibody (B-3) Alexa Fluor® 546 | sc-374138 AF546 | 200 µg/ml | $357.00 | |||
ELOVL5 Antibody (B-3) Alexa Fluor® 594 | sc-374138 AF594 | 200 µg/ml | $357.00 | |||
ELOVL5 Antibody (B-3) Alexa Fluor® 647 | sc-374138 AF647 | 200 µg/ml | $357.00 | |||
ELOVL5 Antibody (B-3) Alexa Fluor® 680 | sc-374138 AF680 | 200 µg/ml | $357.00 | |||
ELOVL5 Antibody (B-3) Alexa Fluor® 790 | sc-374138 AF790 | 200 µg/ml | $357.00 |