Elk-1 Antibody (3H6D12): sc-65986

Elk-1 Antibody (3H6D12) is a mouse monoclonal IgG1 kappa light chain antibody, designed to target the human Elk-1 protein. Elk-1, also known as SAP-2, is a crucial member of the Ets family of transcription factors that plays a significant role in regulating gene expression involved in cell proliferation, differentiation, and stress responses. Located predominantly in the nucleus, Elk-1′s nuclear localization is essential for binding to DNA and modulating the transcription of immediate early genes such as c-Fos, which are pivotal in cellular responses to growth signals and MAPK/ERK signaling pathways. Anti-Elk-1 antibody (3H6D12) is raised against a purified truncated recombinant form of human Elk-1. Elk-1 (3H6D12) antibody is validated for use in multiple applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP), demonstrating broad reactivity with human Elk-1. The precise detection of Elk-1′s localization and expression levels is vital for studies investigating signaling pathways and oncogenic processes where Elk-1 is implicated. Anti-Elk-1 antibody (3H6D12) enables researchers to achieve reliable and accurate insights into the cellular mechanisms governed by this important transcription factor, facilitating advancements in understanding disease states and developing targeted therapies.

The preferred p-Elk-1 antibody is p-Elk-1 Antibody (B-4): sc-8406.