
eIF5 Antibody (A-3) is a mouse monoclonal IgG2b antibody that detects eIF5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). eIF5 plays a crucial role in the regulation of translation initiation, a vital process for cellular function and growth, as eIF5 catalyzes the hydrolysis of GTP bound to the 40S ribosomal subunit, facilitating the assembly of the 80S initiation complex necessary for protein synthesis. Proper functioning of eIF5 is essential because dysregulation in translation initiation can lead to various diseases, including cancer, where overexpression of initiation factors can contribute to uncontrolled cell proliferation. eIF5 interacts with other initiation factors, such as eIF-2 and eIF-4E, forming a complex that is critical for the recruitment of ribosomal subunits and translation initiation. anti-eIF5 antibody (A-3) serves as an invaluable tool for researchers studying translation regulation mechanisms and disease implications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eIF5 Antibody (A-3) | sc-48419 | 200 µg/ml | $322.00 | |||
eIF5 Antibody (A-3): m-IgG Fc BP-HRP Bundle | sc-536839 | 200 µg Ab; 10 µg BP | $361.00 | |||
eIF5 Antibody (A-3): m-IgGκ BP-HRP Bundle | sc-534006 | 200 µg Ab; 40 µg BP | $361.00 | |||
eIF5 Antibody (A-3): m-IgG2b BP-HRP Bundle | sc-549835 | 200 µg Ab; 10 µg BP | $361.00 |