eIF3ε Antibody (H-4): sc-514292

eIF3ε Antibody (H-4) is a mouse monoclonal IgG2b antibody that detects eIF3ε in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). eIF3ε is a crucial component of the eukaryotic initiation factor 3 complex, which plays a vital role in the regulation of protein synthesis by facilitating the assembly of the 40S ribosomal subunit. eIF3ε is located in the cytoplasm, where eIF3ε interacts with other initiation factors and mRNA to form the pre-initiation complex, a necessary step for the translation process. Proper localization of eIF3ε is essential for efficient protein synthesis, as eIF3ε ensures that the ribosomal subunits are correctly assembled and that translation initiation occurs smoothly. Dysregulation of eIF3ε has been implicated in various cancers, highlighting eIF3ε′s importance not only in normal cellular function but also in the pathology of tumorigenesis. With its ability to provide insights into the mechanisms of protein synthesis and potential role in cancer, anti-eIF3ε antibody (H-4) is an invaluable tool for researchers studying these critical biological processes.

The preferred eIF3ε antibody is eIF3ε Antibody (G-7): sc-390413.