eIF3β Antibody (B-6): sc-271539
- eIF3β Antibody (B-6) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 215-242 near the C-terminus of eIF3β of human origin
- recommended for detection of eIF3β of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and avian
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for eIF3β Antibody (B-6) for WB applications. These reagents are now offered in bundles with eIF3β Antibody (B-6) (see ordering information below).
eIF3β Antibody (B-6) is a mouse monoclonal IgG1 antibody that detects eIF3β in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). eIF3β is a crucial component of the eukaryotic initiation factor 3 complex, which plays a vital role in regulating protein synthesis by facilitating 40S ribosomal subunit assembly. eIF3β is located in the cytoplasm, where eIF3β interacts with other initiation factors and mRNA to form the pre-initiation complex necessary for translation. Proper localization of eIF3β is essential for efficient protein synthesis, ensuring ribosomal subunits are correctly assembled and translation initiation occurs smoothly. Dysregulation of eIF3β has been implicated in various cancers, highlighting eIF3β′s importance not only in normal cellular function but also in tumor development. With insights into protein synthesis mechanisms and potential cancer involvement, anti-eIF3β antibody (B-6) serves as an invaluable tool for researchers studying these critical biological processes.
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eIF3β Antibody (B-6) References:
- RNA interference-mediated silencing of eukaryotic translation initiation factor 3, subunit B (EIF3B) gene expression inhibits proliferation of colon cancer cells. | Wang, Z., et al. 2012. World J Surg Oncol. 10: 119. PMID: 22734884
- Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor β1-3 (TGF-β1-3). | Yue, MM., et al. 2014. J Biol Chem. 289: 33971-83. PMID: 25336651
- Expression of eukaryotic translation initiation factor 3 subunit B in liver cancer and its prognostic significance. | Yue, Q., et al. 2020. Exp Ther Med. 20: 436-446. PMID: 32537008
- Eukaryotic translation initiation factor 3 subunit b is a novel oncogenic factor in prostate cancer. | Xiang, P., et al. 2020. Mamm Genome. 31: 197-204. PMID: 32556998
- Attenuated diphtheria toxin mediates siRNA delivery. | Arnold, AE., et al. 2020. Sci Adv. 6: PMID: 32917630
- Eukaryotic Translation Initiation Factor 3 Subunit B Is a Promoter in the Development and Progression of Pancreatic Cancer. | Ren, H., et al. 2021. Front Oncol. 11: 644156. PMID: 33996561
- Eukaryotic translation initiation factor 3 subunit B could serve as a potential prognostic predictor for breast cancer. | Song, S., et al. 2022. Bioengineered. 13: 2762-2776. PMID: 35040374
- Eukaryotic translation initiation factor 3 subunit B promotes head and neck cancer via CEBPB translation. | Xu, C., et al. 2022. Cancer Cell Int. 22: 161. PMID: 35459206
- YTHDF2 Is a Therapeutic Target for HCC by Suppressing Immune Evasion and Angiogenesis Through ETV5/PD-L1/VEGFA Axis. | Wen, J., et al. 2024. Adv Sci (Weinh). 11: e2307242. PMID: 38247171
- New TIPARP inhibitor rescues mitochondrial function and brain injury in ischemic stroke. | Cai, Y., et al. 2024. Pharmacol Res. 210: 107508. PMID: 39547463
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eIF3β Antibody (B-6) | sc-271539 | 200 µg/ml | $316.00 | |||
eIF3β Antibody (B-6): m-IgG Fc BP-HRP Bundle | sc-537658 | 200 µg Ab; 10 µg BP | $354.00 | |||
eIF3β Antibody (B-6): m-IgGκ BP-HRP Bundle | sc-534992 | 200 µg Ab; 40 µg BP | $354.00 | |||
eIF3β Antibody (B-6): m-IgG1 BP-HRP Bundle | sc-545287 | 200 µg Ab; 20 µg BP | $354.00 | |||
eIF3β (B-6) Neutralizing Peptide | sc-271539 P | 100 µg/0.5 ml | $68.00 |