eIF2β Antibody (E-4): sc-166536
- eIF2β Antibody (E-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against a peptide mapping at the N-terminus of eIF2β of human origin
- recommended for detection of eIF2β of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for eIF2β Antibody (E-4) for WB applications. These reagents are now offered in bundles with eIF2β Antibody (E-4) (see ordering information below).
eIF2β Antibody (E-4) is a mouse monoclonal IgG1 antibody that detects eIF2β in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). eIF2β, a critical component of the eukaryotic translation initiation complex, plays a vital role in the regulation of protein synthesis by facilitating the exchange of GDP for GTP on the eIF2 complex, which is essential for the recruitment of the ribosomal subunit during translation initiation. The eIF2β subunit enhances the guanine nucleotide exchange factor activity of the entire eIF2B complex, ensuring efficient protein synthesis under normal cellular conditions. Additionally, phosphorylation of eIF2, which can inhibit the guanine nucleotide exchange factor activity of eIF2B, highlights the regulatory mechanisms that control protein synthesis in response to stress, making eIF2β a key player in maintaining cellular homeostasis. Anti-eIF2β antibody (E-4) serves as an invaluable tool for researchers studying translation regulation and its implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eIF2β Antibody (E-4) | sc-166536 | 200 µg/ml | $316.00 | |||
eIF2β Antibody (E-4): m-IgG Fc BP-HRP Bundle | sc-537502 | 200 µg Ab; 10 µg BP | $354.00 | |||
eIF2β Antibody (E-4): m-IgGκ BP-HRP Bundle | sc-534784 | 200 µg Ab; 40 µg BP | $354.00 | |||
eIF2β Antibody (E-4): m-IgG1 BP-HRP Bundle | sc-545205 | 200 µg Ab; 20 µg BP | $354.00 | |||
eIF2β (E-4) Neutralizing Peptide | sc-166536 P | 100 µg/0.5 ml | $68.00 |