eIF2Bδ Antibody (H-4): sc-271795
- eIF2Bδ Antibody (H-4) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 224-503 mapping near the C-terminus of eIF2Bδ of human origin
- recommended for detection of eIF2Bδ of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for eIF2Bδ Antibody (H-4) for WB applications. These reagents are now offered in bundles with eIF2Bδ Antibody (H-4) (see ordering information below).
eIF2Bδ Antibody (H-4) is a mouse monoclonal IgG1 antibody that detects eIF2Bδ in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). eIF2Bδ is a crucial component of the eukaryotic initiation factor 2B complex, which plays a vital role in the regulation of protein synthesis by facilitating the exchange of GDP for GTP on the eIF2 complex. This exchange is essential for the proper assembly of the translation initiation complex, allowing for the accurate initiation of protein synthesis. The eIF2B complex, consisting of five subunits including eIF2Bδ, ensures that the translation process is tightly regulated, responding to cellular stress and nutrient availability. Notably, the phosphorylation of eIF2 can inhibit the guanine nucleotide exchange factor activity of the eIF2B complex, which is a critical mechanism for controlling protein synthesis under stress conditions. Anti-eIF2Bδ antibody (H-4) enables researchers to gain insights into the dynamics of protein synthesis regulation and its implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
eIF2Bδ Antibody (H-4) | sc-271795 | 200 µg/ml | $322.00 | |||
eIF2Bδ Antibody (H-4): m-IgG Fc BP-HRP Bundle | sc-537694 | 200 µg Ab; 10 µg BP | $361.00 | |||
eIF2Bδ Antibody (H-4): m-IgGκ BP-HRP Bundle | sc-535042 | 200 µg Ab; 40 µg BP | $361.00 | |||
eIF2Bδ Antibody (H-4): m-IgG1 BP-HRP Bundle | sc-545312 | 200 µg Ab; 20 µg BP | $361.00 |