EFP Antibody (D-8): sc-398817

EFP Antibody (D-8) is a mouse monoclonal IgG2a light chain antibody that detects EFP (estrogen-responsive finger protein) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EFP plays a crucial role as a transcription factor regulated by estrogen, a hormone essential for various physiological processes, including growth and differentiation in target cells across multiple tissues. EFP (D-8) antibody recognizes a member of the RING finger family, characterized by a zinc-binding domain, featuring two B box domains along with a coiled-coil region that serves as a transactivation domain. This structural composition allows anti-EFP antibody (D-8) to detect proteins that facilitate the transcription of secondary estrogen-responsive genes, thereby amplifying the cellular response to estrogen. The regulation of EFP expression involves multiple elements and their interacting factors, which underscores its importance in mediating estrogen′s effects within the cell. EFP monoclonal antibody (D-8) serves as an invaluable tool for researchers exploring the intricate mechanisms of estrogen signaling and its impact on gene regulation.

The preferred EFP antibody is EFP Antibody (E-4): sc-166926.