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EAG Antibody (G-3) is a mouse monoclonal IgG2b antibody that detects EAG protein of Streptococcus equi by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-EAG antibody (G-3) specifically targets EAG protein, a 429 amino acid molecule known for binding to immunoglobulins, alpha2-macroglobulin, and albumin, thereby playing a crucial part in the immune evasion strategies of S. equi. EAG protein′s ability to interact with host immune components is significant as this interaction allows the pathogen to persist and cause disease, particularly in young horses whose immune systems are still developing. EAG presence in the extracellular environment of the pathogen facilitates survival by modulating the host′s immune response, leading to characteristic symptoms of strangles, such as lymphadenopathy, fever, and nasal discharge. EAG (G-3) antibody is an essential tool for researchers studying the pathogenesis of S. equi and immune responses in equine health, providing insights that could lead to better prevention and treatment strategies for this infectious disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EAG Antibody (G-3) | sc-377242 | 200 µg/ml | $316.00 |