Date published: 2025-12-24

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EAG Antibody (G-3): sc-377242

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Datasheets
  • EAG Antibody (G-3) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
  • raised against amino acids 1-429 representing full length EAG of Streptococcus equi subsp. equi origin
  • recommended for detection of S. equi by WB, IP, IF and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for EAG Antibody (G-3). This work is in progress.

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    EAG Antibody (G-3) is a mouse monoclonal IgG2b antibody that detects EAG protein of Streptococcus equi by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-EAG antibody (G-3) specifically targets EAG protein, a 429 amino acid molecule known for binding to immunoglobulins, alpha2-macroglobulin, and albumin, thereby playing a crucial part in the immune evasion strategies of S. equi. EAG protein′s ability to interact with host immune components is significant as this interaction allows the pathogen to persist and cause disease, particularly in young horses whose immune systems are still developing. EAG presence in the extracellular environment of the pathogen facilitates survival by modulating the host′s immune response, leading to characteristic symptoms of strangles, such as lymphadenopathy, fever, and nasal discharge. EAG (G-3) antibody is an essential tool for researchers studying the pathogenesis of S. equi and immune responses in equine health, providing insights that could lead to better prevention and treatment strategies for this infectious disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    EAG Antibody (G-3)

    sc-377242
    200 µg/ml
    $316.00

    For Western Blot, is it recommended to use denatured or non-denatured conditions with EAG (G-3): sc-377242 monoclonal antibody?

    Asked by: Randy McDonald
    Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western blot data of StreptococcusProduced positive Western blot data of Streptococcus equi recombinant EAG (FL-429), EAG (amino acids 215-429) and EAG (amino acids 1-214) fusion proteins. -SCBT QC
    Date published: 2013-09-24
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    EAG Antibody (G-3) is rated 5.0 out of 5 by 1.
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