DYNC2LI1 Antibody (H-4): sc-376644
- DYNC2LI1 Antibody (H-4) is a mouse monoclonal IgG1 κ DYNC2LI1 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 65-97 within a cytoplasmic domain of DYNC2LI1 of human origin
- DYNC2LI1 Antibody (H-4) is recommended for detection of DYNC2LI1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-DYNC2LI1 Antibody (H-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of DYNC2LI1 (H-4): sc-376644.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for DYNC2LI1 Antibody (H-4) for WB applications. These reagents are now offered in bundles with DYNC2LI1 Antibody (H-4) (see ordering information below).
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DYNC2LI1 Antibody (H-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects DYNC2LI1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-DYNC2LI1 antibody (H-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. DYNC2LI1, also known as dynein, cytoplasmic 2, light intermediate chain 1, plays a crucial role in cellular processes by functioning as a motor for intraflagellar retrograde transport and contributing to cilia biogenesis. This 351 amino acid protein is part of the dynein light intermediate chain family and is essential for the assembly and transport of organelles within the cell, which is vital for maintaining cellular homeostasis and function. The cytoplasmic dynein complex, which includes DYNC2LI1, is composed of multiple subunits, including heavy chains and light chains, and is responsible for converting the chemical energy of ATP into mechanical movement along microtubules. DYNC2LI1 exists in five alternatively spliced isoforms, highlighting its versatility and importance in various cellular contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
DYNC2LI1 Antibody (H-4) References:
- Identification of a novel light intermediate chain (D2LIC) for mammalian cytoplasmic dynein 2. | Grissom, PM., et al. 2002. Mol Biol Cell. 13: 817-29. PMID: 11907264
- Cytoplasmic dynein functions as a gear in response to load. | Mallik, R., et al. 2004. Nature. 427: 649-52. PMID: 14961123
- Cytoplasmic dynein nucleates microtubules to organize them into radial arrays in vivo. | Malikov, V., et al. 2004. Mol Biol Cell. 15: 2742-9. PMID: 15047865
- High speed sliding of axonemal microtubules produced by outer arm dynein. | Seetharam, RN. and Satir, P. 2005. Cell Motil Cytoskeleton. 60: 96-103. PMID: 15605357
- The offloading model for dynein function: differential function of motor subunits. | Lee, WL., et al. 2005. J Cell Biol. 168: 201-7. PMID: 15642746
- Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments. | He, Y., et al. 2005. J Cell Biol. 168: 697-703. PMID: 15728192
- Cytoplasmic dynein nomenclature. | Pfister, KK., et al. 2005. J Cell Biol. 171: 411-3. PMID: 16260502
- Dynein motility: four heads are better than two. | McGrath, JL. 2005. Curr Biol. 15: R970-2. PMID: 16332531
- Genetic analysis of the cytoplasmic dynein subunit families. | Pfister, KK., et al. 2006. PLoS Genet. 2: e1. PMID: 16440056
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DYNC2LI1 Antibody (H-4) | sc-376644 | 200 µg/ml | $316.00 | |||
DYNC2LI1 Antibody (H-4): m-IgG Fc BP-HRP Bundle | sc-529914 | 200 µg Ab; 10 µg BP | $354.00 | |||
DYNC2LI1 Antibody (H-4): m-IgGκ BP-HRP Bundle | sc-523032 | 200 µg Ab, 40 µg BP | $354.00 | |||
DYNC2LI1 Antibody (H-4): m-IgG1 BP-HRP Bundle | sc-543761 | 200 µg Ab; 20 µg BP | $354.00 | |||
DYNC2LI1 Antibody (H-4) AC | sc-376644 AC | 500 µg/ml, 25% agarose | $416.00 | |||
DYNC2LI1 Antibody (H-4) HRP | sc-376644 HRP | 200 µg/ml | $316.00 | |||
DYNC2LI1 Antibody (H-4) FITC | sc-376644 FITC | 200 µg/ml | $330.00 | |||
DYNC2LI1 Antibody (H-4) PE | sc-376644 PE | 200 µg/ml | $343.00 | |||
DYNC2LI1 Antibody (H-4) Alexa Fluor® 488 | sc-376644 AF488 | 200 µg/ml | $357.00 | |||
DYNC2LI1 Antibody (H-4) Alexa Fluor® 546 | sc-376644 AF546 | 200 µg/ml | $357.00 | |||
DYNC2LI1 Antibody (H-4) Alexa Fluor® 594 | sc-376644 AF594 | 200 µg/ml | $357.00 | |||
DYNC2LI1 Antibody (H-4) Alexa Fluor® 647 | sc-376644 AF647 | 200 µg/ml | $357.00 | |||
DYNC2LI1 Antibody (H-4) Alexa Fluor® 680 | sc-376644 AF680 | 200 µg/ml | $357.00 | |||
DYNC2LI1 Antibody (H-4) Alexa Fluor® 790 | sc-376644 AF790 | 200 µg/ml | $357.00 | |||
DYNC2LI1 (H-4) Neutralizing Peptide | sc-376644 P | 100 µg/0.5 ml | $68.00 |