Dynamin II Antibody (B-2): sc-166526
- Dynamin II Antibody (B-2) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 853-870 at the C-terminus of Dynamin II of human origin
- recommended for detection of Dynamin II of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, bovine, porcine and canine; may cross-react with Dynamin III
- See Dynamin II (G-4): sc-166669 for Dynamin II antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Dynamin II Antibody (B-2) for WB applications. This reagent is now offered in a bundle with Dynamin II Antibody (B-2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Dynamin II Antibody (B-2) is a mouse monoclonal IgG1 antibody that detects Dynamin II in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dynamin II plays a crucial role in cellular processes, particularly in endocytosis, where Dynamin II facilitates the scission of newly formed vesicles from the plasma membrane, thereby regulating the internalization of various receptors and signaling molecules. This function is vital for maintaining cellular homeostasis and communication, as Dynamin II allows cells to respond to external stimuli by modulating receptor availability on the cell surface. Additionally, Dynamin II is ubiquitously distributed throughout the body, with the highest expression levels found in the testis, indicating Dynamin II′s importance in reproductive biology. Dynamin II contains specific domains that enable interaction with various effectors, including microtubules and SH3 domain-containing proteins, which are essential for GTPase activity and the rapid endocytic process. Anti-Dynamin II antibody (B-2) enables researchers to gain insights into the dynamics of endocytosis and its implications in various physiological and pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dynamin II Antibody (B-2) | sc-166526 | 200 µg/ml | $322.00 | |||
Dynamin II Antibody (B-2): m-IgGκ BP-HRP Bundle | sc-551981 | 200 µg Ab; 40 µg BP | $361.00 | |||
Dynamin II (B-2) Neutralizing Peptide | sc-166526 P | 100 µg/0.5 ml | $69.00 |