Dvl-2/Dishevelled 2/DVL2 Antibody (D-6): sc-390303

Dvl-2 Antibody (D-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects Dvl-2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dvl-2 (D-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Dvl-2 plays a crucial role in the Wnt signaling pathway, which is essential for various cellular processes, including cell proliferation, differentiation, and embryonic development. Specifically, Dvl-2 acts as a key mediator in the transduction of Wnt signals, influencing the regulation of gene expression and cellular behavior. Proper functioning of Dvl-2 is vital, as dysregulation of the Wnt pathway has been implicated in numerous diseases, including cancer and neurodegenerative disorders. Mammalian dishevelled proteins, including Dvl-2, share structural similarities with the Drosophila dishevelled protein and contain three homologous domains, two of which are unique to this family. The third domain is homologous to the discs-large homology domain of the Drosophila tumor suppressor protein, suggesting a conserved role in cellular signaling and development. Understanding Dvl-2 function and interactions is critical for elucidating contributions to both normal physiology and disease states.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Dvl-2/Dishevelled 2/DVL2 Antibody (D-6) has 5 citations in a variety of scientific publications.

Primary antibodies like Anti-Dvl-2/Dishevelled 2/DVL2 Antibody (D-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Dvl-2/Dishevelled 2/DVL2 Antibody (D-6) Specifications

Alternate Product Name: DVL2

Product Clone Name: D-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 2-29

Epitope Target: Dvl-2

Epitope Species: human

Product Reactivity/Detection: Dvl-2

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 5 citations in various scientific publications

Available Conjugates/Forms for Dvl-2/Dishevelled 2/DVL2 Antibody (D-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred Dvl-2/Dishevelled 2/DVL2 antibody is Dvl-2/Dishevelled 2/DVL2 Antibody (10B5): sc-8026.