| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Pyrvinium Pamoate | 3546-41-6 | sc-476920A sc-476920 | 250 mg 500 mg | $228.00 $422.00 | ||
Downregulates Dvl-2 levels, potentially inhibiting Wnt signaling and reducing cell proliferation in colorectal cancer cells and other Wnt-dependent malignancies. | ||||||
KY02111 | 1118807-13-8 | sc-397043 sc-397043A | 5 mg 25 mg | $79.00 $336.00 | ||
Antagonizes Dvl-2 by inhibiting its interaction with Axin, disrupting the formation of the destruction complex and potentially modulating Wnt signaling and cell fate determination. | ||||||
β-Catenin/Tcf Inhibitor, FH535 | 108409-83-2 | sc-221398 sc-221398A | 10 mg 50 mg | $182.00 $374.00 | 7 | |
Inhibits Dvl-2 and its downstream β-catenin/Tcf interaction, disrupting the canonical Wnt pathway and potentially attenuating cell proliferation and tumorigenesis. | ||||||
IWR-1-endo | 1127442-82-3 | sc-295215 sc-295215A | 5 mg 10 mg | $82.00 $135.00 | 19 | |
Antagonizes Dvl-2 by promoting its interaction with Axin, leading to degradation of Dvl-2 and inhibition of the canonical Wnt pathway and its associated cellular processes. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $36.00 $117.00 $525.00 | 26 | |
Targets tankyrase, inhibiting poly-ADP-ribosylation of Axin and leading to its stabilization, which in turn inhibits Dvl-2 activity and the canonical Wnt signaling pathway. | ||||||