Dicer Antibody (E-7): sc-393328
- Dicer Antibody (E-7) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1698-1729 near the C-terminus of Dicer of human origin
- recommended for detection of Dicer of mouse, rat and human origin by WB, IP, IF and ELISA
- See Dicer (F-10): sc-136979 for Dicer antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Dicer Antibody (E-7) for WB applications. These reagents are now offered in bundles with Dicer Antibody (E-7) (see ordering information below).
QUICK LINKS
SEE ALSO...
Dicer Antibody (E-7) is a mouse monoclonal IgG2a antibody that detects Dicer in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Dicer is a crucial component of the RNA interference pathway, playing a vital role in the processing of small RNA molecules that regulate gene expression. Dicer is primarily located in the cytoplasm of mammalian cells, where Dicer co-localizes with calreticulin in the endoplasmic reticulum, highlighting Dicer′s importance in cellular RNA metabolism. Dicer′s localization allows for efficient processing of precursor microRNAs and short hairpin RNAs into functional small interfering RNAs, which are essential for targeted degradation of homologous mRNAs. Dicer′s ability to cleave RNA precursors into 21-23 base pair double-stranded RNAs is critical for gene expression regulation and maintaining cellular homeostasis. Additionally, Dicer′s interaction with translation initiation factors, such as the PIWI domain of eIF2C, underscores Dicer′s role in RNA processing and gene silencing mechanisms. With diverse applications and essential functions, anti-Dicer antibody (E-7) serves as an invaluable tool for researchers studying RNA interference and gene regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Dicer Antibody (E-7) | sc-393328 | 200 µg/ml | $322.00 | |||
Dicer Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-538190 | 200 µg Ab; 10 µg BP | $361.00 | |||
Dicer Antibody (E-7): m-IgGκ BP-HRP Bundle | sc-535754 | 200 µg Ab; 40 µg BP | $361.00 | |||
Dicer Antibody (E-7): m-IgG2a BP-HRP Bundle | sc-548228 | 200 µg Ab; 10 µg BP | $361.00 | |||
Dicer (E-7) Neutralizing Peptide | sc-393328 P | 100 µg/0.5 ml | $69.00 |