Desmin Antibody (B-12): sc-365130
- Desmin Antibody (B-12) is a mouse monoclonal IgA κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 413-445 near the C-terminus of Desmin of human origin
- recommended for detection of Desmin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine
- See Desmin (RD301): sc-23879 for Desmin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Desmin Antibody (B-12). This work is in progress.
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SEE ALSO...
Desmin Antibody (B-12) is a mouse monoclonal IgA antibody that detects Desmin in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Desmin is a crucial intermediate filament protein that plays a significant role in maintaining the structural integrity of muscle cells. Desmin is primarily located near the Z line in sarcomeres, where Desmin forms a network that connects adjacent myofibrils, thereby facilitating the transmission of force during muscle contraction. This structural organization is vital for muscle function, as Desmin ensures that contractile forces generated by sarcomeres are effectively transmitted throughout the muscle fiber. Additionally, proper assembly and function of Desmin are essential for overall muscle tissue health; mutations in the gene encoding Desmin can lead to severe conditions such as adult-onset skeletal myopathy and cardiac issues. Anti-Desmin antibody (B-12) is an invaluable tool for researchers studying muscle development, pathology, and underlying mechanisms of muscle-related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Desmin Antibody (B-12) | sc-365130 | 200 µg/ml | $322.00 | |||
Desmin (B-12) Neutralizing Peptide | sc-365130 P | 100 µg/0.5 ml | $69.00 |