DDR1 Antibody (D-10): sc-390268

DDR1 Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects discoidin domain receptor 1 (DDR1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DDR1 is a member of the receptor tyrosine kinase family, which plays a crucial role in mediating cellular responses to the extracellular matrix, particularly collagen. The activation of DDR1 by collagen initiates a cascade of intracellular signaling pathways that influence cell adhesion, migration, and proliferation, thereby impacting tissue remodeling and repair processes. Notably, DDR1′s interaction with collagen not only activates downstream signaling but also facilitates the phosphorylation of specific docking sites, which are essential for recruiting signaling proteins like Shc, further amplifying the cellular response. Anti-DDR1 antibody (D-10) is an invaluable tool for researchers studying the intricate mechanisms of cell-matrix interactions and their implications in various physiological and pathological conditions.

The preferred DDR1 antibody is DDR1 Antibody (C-6): sc-374618.