DDR 抗体和相关产品
圣克鲁斯生物技术公司提供一系列全面的 DDR 抗体，用于研究 DNA 损伤反应机制。DDR 抗体与多种应用兼容，包括免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组化 (IHCP)、流式细胞术 (FCM) 和酶联免疫吸附试验 (ELISA)。DNA 损伤应答（DDR）是一个关键的细胞过程，它能检测和修复 DNA 病变，确保基因组的稳定性，防止癌症等疾病的发生。了解 DNA 损伤应答机制有助于深入了解细胞对基因毒性应激的反应以及肿瘤发生的内在机制。DDR 研究不断揭示影响细胞存活和疾病进展的新途径和分子相互作用。对 DNA 损伤应答途径的研究已在癌症生物学和治疗开发方面取得重大突破。该领域的研究拓展了我们对细胞修复机制及其对人类健康影响的认识。圣克鲁斯生物技术公司的 DDR 单克隆抗体使全球研究人员能够推进对 DNA 修复机制的科学理解，并促进创新治疗策略的开发。
DDR 抗体
| Empty Table Header | 产品名称 | 目录 | 亚型 | 抗原决定簇 | 应用 | Species | 应用 | 排名 |
|---|---|---|---|---|---|---|---|---|
DDR1 抗体 (C-6) | sc-374618 | mouse IgG2b κ | C-Terminal (h) | WB, IP, IF, ELISA | h | 5 | ||
DDR1 抗体 (48B3) | sc-21790 | mouse IgM κ | FL (h) | WB, IP, IF, IHC(P), FCM | h | 6 | ||
DDR1 抗体 (D-10) | sc-390268 | mouse IgG1 κ | 291-416 (h) | WB, IP, IF, ELISA | m, r, h | 3 | ||
DDR2 抗体 (3B11E4) | sc-81707 | mouse IgG2a κ | 422-639 (h) | WB, IP, IF, IHC(P) | m, r, h | 9 |
DDR CRISPR 敲除，HDR 和双切口酶质粒
| Empty Table Header | 产品名称 | 目录 | Species | 应用 | 标记物 | 应用 | 排名 |
|---|---|---|---|---|---|---|---|
DDR1 CRISPR/Cas9 KO质粒 (h) | sc-400517 | h | Gene Knockout | GFP | 0 | ||
DDR1 HDR 质粒 (h) | sc-400517-HDR | h | Homology Directed Repair | Puromycin | 0 | ||
DDR1双切口酶质粒(h) | sc-400517-NIC | h | Gene Knockout | Puromycin | 0 | ||
DDR1双切口酶质粒(h2) | sc-400517-NIC-2 | h | Gene Knockout | Puromycin | 0 | ||
DDR1 CRISPR/Cas9 KO质粒 (m) | sc-419417 | m | Gene Knockout | GFP | 0 | ||
DDR1 HDR 质粒 (m) | sc-419417-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
DDR1双切口酶质粒(m) | sc-419417-NIC | m | Gene Knockout | Puromycin | 0 | ||
DDR1双切口酶质粒(m2) | sc-419417-NIC-2 | m | Gene Knockout | Puromycin | 0 | ||
DDR2 CRISPR/Cas9 KO质粒 (h) | sc-400414 | h | Gene Knockout | GFP | 0 | ||
DDR2 HDR 质粒 (h) | sc-400414-HDR | h | Homology Directed Repair | Puromycin | 0 | ||
DDR2双切口酶质粒(h) | sc-400414-NIC | h | Gene Knockout | Puromycin | 0 | ||
DDR2双切口酶质粒(h2) | sc-400414-NIC-2 | h | Gene Knockout | Puromycin | 0 | ||
DDR2 CRISPR/Cas9 KO质粒 (m) | sc-421985 | m | Gene Knockout | GFP | 0 | ||
DDR2 HDR 质粒 (m) | sc-421985-HDR | m | Homology Directed Repair | Puromycin | 0 | ||
DDR2双切口酶质粒(m) | sc-421985-NIC | m | Gene Knockout | Puromycin | 0 | ||
DDR2双切口酶质粒(m2) | sc-421985-NIC-2 | m | Gene Knockout | Puromycin | 0 |
DDR CRISPR 激活产品
| Empty Table Header | 产品名称 | 目录 | Species | 应用 | 标记物 | 应用 | 排名 |
|---|---|---|---|---|---|---|---|
DDR1CRISPR激活质粒(h) | sc-400517-ACT | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR1CRISPR激活质粒(h2) | sc-400517-ACT-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR1慢病毒激活颗粒(h) | sc-400517-LAC | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR1慢病毒激活颗粒(h2) | sc-400517-LAC-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR1CRISPR激活质粒(m) | sc-419417-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR1CRISPR激活质粒(m2) | sc-419417-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR1慢病毒激活颗粒(m) | sc-419417-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR1慢病毒激活颗粒(m2) | sc-419417-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2CRISPR激活质粒(h) | sc-400414-ACT | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2CRISPR激活质粒(h2) | sc-400414-ACT-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2慢病毒激活颗粒(h) | sc-400414-LAC | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2慢病毒激活颗粒(h2) | sc-400414-LAC-2 | h | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2CRISPR激活质粒(m) | sc-421985-ACT | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2CRISPR激活质粒(m2) | sc-421985-ACT-2 | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2慢病毒激活颗粒(m) | sc-421985-LAC | m | Gene Activation | Puro, Blast, Hygro | 0 | ||
DDR2慢病毒激活颗粒(m2) | sc-421985-LAC-2 | m | Gene Activation | Puro, Blast, Hygro | 0 |
DDR siRNA, shRNA 质粒和 shRNA 慢病毒颗粒基因沉默产品
| Empty Table Header | 产品名称 | 目录 | Species | 应用 | 标记物 | 应用 | 排名 |
|---|---|---|---|---|---|---|---|
DDR1 siRNA (h) | sc-35187 | h | Gene Silencing | N/A | 11 | ||
DDR1 shRNA 质粒 (h) | sc-35187-SH | h | Gene Silencing | Puromycin | 11 | ||
DDR1 shRNA (h) 慢病毒颗粒 | sc-35187-V | h | Gene Silencing | Puromycin | 11 | ||
DDR1 siRNA (m) | sc-35188 | m | Gene Silencing | N/A | 0 | ||
DDR1 shRNA 质粒 (m) | sc-35188-SH | m | Gene Silencing | Puromycin | 0 | ||
DDR1 shRNA (m) 慢病毒颗粒 | sc-35188-V | m | Gene Silencing | Puromycin | 0 | ||
DDR2 siRNA (h) | sc-39922 | h | Gene Silencing | N/A | 3 | ||
DDR2 shRNA 质粒 (h) | sc-39922-SH | h | Gene Silencing | Puromycin | 3 | ||
DDR2 shRNA (h) 慢病毒颗粒 | sc-39922-V | h | Gene Silencing | Puromycin | 3 | ||
DDR2 siRNA (m) | sc-39923 | m | Gene Silencing | N/A | 4 | ||
DDR2 shRNA 质粒 (m) | sc-39923-SH | m | Gene Silencing | Puromycin | 4 | ||
DDR2 shRNA (m) 慢病毒颗粒 | sc-39923-V | m | Gene Silencing | Puromycin | 4 | ||
DDR2 siRNA (r) | sc-108075 | r | Gene Silencing | N/A | 0 | ||
DDR2 shRNA 质粒 (r) | sc-108075-SH | r | Gene Silencing | Puromycin | 0 | ||
DDR2 shRNA (r) 慢病毒颗粒 | sc-108075-V | r | Gene Silencing | Puromycin | 0 |