Date published: 2026-4-26

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DDR Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of DDR Antibodies for investigating DNA damage response mechanisms. DDR Antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The DNA damage response (DDR) is a critical cellular process that detects and repairs DNA lesions, ensuring genomic stability and preventing the onset of diseases such as cancer. Understanding DNA damage response mechanisms provides insights into cellular responses to genotoxic stress and the mechanisms underlying tumorigenesis. DDR research continues to reveal new pathways and molecular interactions that influence cell survival and disease progression. Investigating DNA damage response pathways has led to significant breakthroughs in cancer biology and therapeutic development. Research in this field has expanded our knowledge of cellular repair mechanisms and their impact on human health. DDR monoclonal antibodies from Santa Cruz Biotechnology enable researchers worldwide to advance scientific understanding of DNA repair mechanisms and contribute to the development of innovative therapeutic strategies.

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DDR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DDR1 Antibody (C-6)

sc-374618mouse IgG2b κC-Terminal (h)WB, IP, IF, ELISAh
5
(4)

DDR1 Antibody (48B3)

sc-21790mouse IgM κFL (h)WB, IP, IF, IHC(P), FCMh
6
(6)

DDR1 Antibody (D-10)

sc-390268mouse IgG1 κ291-416 (h)WB, IP, IF, ELISAm, r, h
3
(1)

DDR2 Antibody (3B11E4)

sc-81707mouse IgG2a κ422-639 (h)WB, IP, IF, IHC(P)m, r, h
9
(6)

DDR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DDR1 CRISPR/Cas9 KO Plasmid (h)

sc-400517hGene KnockoutGFP0
(0)

DDR1 HDR Plasmid (h)

sc-400517-HDRhHomology Directed RepairPuromycin0
(0)

DDR1 Double Nickase Plasmid (h)

sc-400517-NIChGene KnockoutPuromycin0
(0)

DDR1 Double Nickase Plasmid (h2)

sc-400517-NIC-2hGene KnockoutPuromycin0
(0)

DDR1 CRISPR/Cas9 KO Plasmid (m)

sc-419417mGene KnockoutGFP0
(0)

DDR1 HDR Plasmid (m)

sc-419417-HDRmHomology Directed RepairPuromycin0
(0)

DDR2 CRISPR/Cas9 KO Plasmid (h)

sc-400414hGene KnockoutGFP0
(0)

DDR2 HDR Plasmid (h)

sc-400414-HDRhHomology Directed RepairPuromycin0
(0)

DDR2 Double Nickase Plasmid (h)

sc-400414-NIChGene KnockoutPuromycin0
(0)

DDR2 Double Nickase Plasmid (h2)

sc-400414-NIC-2hGene KnockoutPuromycin0
(0)

DDR2 CRISPR/Cas9 KO Plasmid (m)

sc-421985mGene KnockoutGFP0
(0)

DDR2 HDR Plasmid (m)

sc-421985-HDRmHomology Directed RepairPuromycin0
(0)

DDR2 Double Nickase Plasmid (m)

sc-421985-NICmGene KnockoutPuromycin0
(0)

DDR2 Double Nickase Plasmid (m2)

sc-421985-NIC-2mGene KnockoutPuromycin0
(0)

DDR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DDR2 CRISPR Activation Plasmid (h)

sc-400414-ACThGene ActivationPuro, Blast, Hygro0
(0)

DDR2 CRISPR Activation Plasmid (h2)

sc-400414-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

DDR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DDR1 siRNA (h)

sc-35187hGene SilencingN/A
11
(0)

DDR1 shRNA Plasmid (h)

sc-35187-SHhGene SilencingPuromycin
11
(0)

DDR1 shRNA (h) Lentiviral Particles

sc-35187-VhGene SilencingPuromycin
11
(0)

DDR1 siRNA (m)

sc-35188mGene SilencingN/A0
(0)

DDR1 shRNA Plasmid (m)

sc-35188-SHmGene SilencingPuromycin0
(0)

DDR1 shRNA (m) Lentiviral Particles

sc-35188-VmGene SilencingPuromycin0
(0)

DDR2 siRNA (h)

sc-39922hGene SilencingN/A
3
(0)

DDR2 shRNA Plasmid (h)

sc-39922-SHhGene SilencingPuromycin
3
(0)

DDR2 shRNA (h) Lentiviral Particles

sc-39922-VhGene SilencingPuromycin
3
(0)

DDR2 siRNA (m)

sc-39923mGene SilencingN/A
4
(0)

DDR2 shRNA Plasmid (m)

sc-39923-SHmGene SilencingPuromycin
4
(0)

DDR2 shRNA (m) Lentiviral Particles

sc-39923-VmGene SilencingPuromycin
4
(0)

DDR2 siRNA (r)

sc-108075rGene SilencingN/A0
(0)

DDR2 shRNA Plasmid (r)

sc-108075-SHrGene SilencingPuromycin0
(0)

DDR2 shRNA (r) Lentiviral Particles

sc-108075-VrGene SilencingPuromycin0
(0)