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DAK Antibody (G-5) is a mouse monoclonal IgM antibody that detects DAK in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). DAK, also known as NET45, is a bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase, consisting of 575 amino acids and belonging to the dihydroxyacetone kinase family. DAK plays a crucial role in cellular metabolism by catalyzing the conversion of FAD to cyclized FMN and facilitating the phosphorylation of dihydroxyacetone, which is essential for energy production and metabolic regulation. DAK exists as a homodimer and contains distinct domains, including the DhaK and DhaL domains, which are vital for its enzymatic functions. The gene encoding DAK is located on human chromosome 11, a region associated with various genetic disorders, including Jervell and Lange-Nielsen syndrome and Niemann-Pick disease, highlighting DAK′s importance in both normal physiology and disease states. DAK Antibody (G-5) serves as an invaluable tool for researchers studying the intricate roles of DAK in metabolic pathways and its implications in human health.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DAK Antibody (G-5) | sc-365984 | 200 µg/ml | $316.00 | |||
DAK (G-5) Neutralizing Peptide | sc-365984 P | 100 µg/0.5 ml | $68.00 |