Cytokeratin 7 Antibody (5F282): sc-70936

Cytokeratin 7 Antibody (5F282) is a mouse monoclonal IgG1 kappa light chain antibody designed to detect Cytokeratin 7, also known as KRT7. Cytokeratin 7 monoclonal antibody (5F282) is raised against T24 cells and demonstrates broad species reactivity, including mouse, rat, human, hamster, canine, and porcine, making it suitable for a variety of applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Cytokeratin 7 is an intermediate filament protein that plays a crucial role in maintaining the structural integrity and resilience of epithelial cells, thereby contributing to tissue differentiation and specialization. The function of Cytokeratin 7 is essential for providing mechanical support to cells, enabling them to withstand stress and maintain their shape, which is vital for the proper functioning of epithelial tissues. Additionally, Cytokeratin 7 serves as an important biomarker in the diagnosis and classification of various cancers, as expression patterns can help distinguish between different tumor types and stages. By utilizing anti-Cytokeratin 7 antibody (5F282), researchers can effectively investigate epithelial cell biology, monitor differentiation processes, and explore the molecular mechanisms underlying cancer progression. Cytokeratin 7′s involvement in intracellular signaling pathways highlights its importance in regulating cell growth and differentiation, underscoring its significance in both normal physiological processes and disease states. With proven performance and broad reactivity, anti-Cytokeratin 7 antibody (5F282) is an essential asset for advancing research and enhancing diagnostic capabilities in various scientific and medical fields.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Cytokeratin 7 Antibody (5F282) has 14 citations in a variety of scientific publications.

Primary antibodies like Anti-Cytokeratin 7 Antibody (5F282) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Cytokeratin 7 Antibody (5F282) Specifications

Alternate Product Name: KRT7

Product Clone Name: 5F282

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: Cytokeratin 7

Epitope Species: human

Product Reactivity/Detection: Cytokeratin 7

Species Reactivity/Detection: mouse, rat, human, hamster, canine, porcine

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), FCM

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 14 citations in various scientific publications

Available Conjugates/Forms for Cytokeratin 7 Antibody (5F282): FITC: Fluoroscein, PE: Phycoerythrin

The preferred Cytokeratin 7 antibody is Cytokeratin 7 Antibody (RCK105): sc-23876.