Cytokeratin 5 Antibody (G-2): sc-377431
- Cytokeratin 5 Antibody (G-2) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 13-47 near the N-terminus of Cytokeratin 5 of human origin
- recommended for detection of Cytokeratin 5 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine and bovine
- See Cytokeratin 5 (RCK103): sc-32721 for Cytokeratin 5 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cytokeratin 5 Antibody (G-2). This work is in progress.
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SEE ALSO...
Cytokeratin 5 Antibody (G-2) is a mouse monoclonal IgG2a antibody that detects Cytokeratin 5 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cytokeratin 5 is a vital component of the cytoskeletal structure in epithelial cells, primarily located in the basal layer of stratified epithelia, where Cytokeratin 5 plays a crucial role in maintaining cellular integrity and resilience against mechanical stress. This localization is particularly important as Cytokeratin 5 contributes to the overall stability of epithelial tissues, which are often subjected to physical abrasion and injury. Furthermore, Cytokeratin 5 expression serves as a key marker for identifying basal cells in various tissues, making anti-Cytokeratin 5 antibody (G-2) invaluable in studying epithelial differentiation and characterizing malignant tumors. Notably, mutations in the gene encoding Cytokeratin 5 (KRT5) can lead to the autosomal dominant disorder epidermolysis bullosa, underscoring Cytokeratin 5′s significance in both health and disease. Anti-Cytokeratin 5 antibody (G-2) serves as an essential tool for researchers investigating epithelial biology and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 5 Antibody (G-2) | sc-377431 | 200 µg/ml | $322.00 | |||
Cytokeratin 5 (G-2) Neutralizing Peptide | sc-377431 P | 100 µg/0.5 ml | $69.00 |