Cytokeratin 5 Antibody (AE14): sc-80606
- Cytokeratin 5 Antibody (AE14) is a mouse monoclonal IgG2b κ, cited in 5 publications, provided at 200 µg/ml
- raised against hair keratins of human origin
- recommended for detection of Cytokeratin 5 of human and bovine origin by WB and IP; may cross-react with some acidic hair cytokeratins
- See Cytokeratin 5 (RCK103): sc-32721 for Cytokeratin 5 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Cytokeratin 5 Antibody (AE14) for WB applications. This reagent is now offered in a bundle with Cytokeratin 5 Antibody (AE14) (see ordering information below).
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SEE ALSO...
Cytokeratin 5 Antibody (AE14) is a mouse monoclonal IgG2b antibody that detects Cytokeratin 5 in human and bovine samples through applications such as western blotting (WB) and immunoprecipitation (IP). Cytokeratin 5 is a vital component of the cytoskeletal structure in epithelial cells, primarily located in the basal layer of stratified epithelia, where Cytokeratin 5 plays a crucial role in maintaining cellular integrity and resilience against mechanical stress. This localization is particularly important as Cytokeratin 5 contributes to the overall stability of epithelial tissues, which are often subjected to physical abrasion and injury. Additionally, Cytokeratin 5 serves as a key marker for identifying basal cell types in various tissues, making anti-Cytokeratin 5 antibody (AE14) invaluable in the study of epithelial differentiation and the characterization of malignant tumors. Mutations in the gene encoding Cytokeratin 5 (KRT5) can lead to severe skin disorders such as epidermolysis bullosa, underscoring Cytokeratin 5′s significance in both health and disease. Cytokeratin 5 (AE14) antibody is therefore an essential tool for researchers investigating epithelial biology and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 5 Antibody (AE14) | sc-80606 | 200 µg/ml | $316.00 | |||
Cytokeratin 5 Antibody (AE14): m-IgG Fc BP-HRP Bundle | sc-551974 | 200 µg Ab; 10 µg BP | $354.00 |