Cytokeratin 19 Antibody (B-1): sc-374192
- Cytokeratin 19 Antibody (B-1) is a mouse monoclonal IgG2b κ, cited in 6 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 7-29 at the N-terminus of Cytokeratin 19 of human origin
- recommended for detection of Cytokeratin 19 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine and porcine
- See Cytokeratin 19 (A-3): sc-376126 for Cytokeratin 19 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Cytokeratin 19 Antibody (B-1) for WB and IHC(P) applications. These reagents are now offered in bundles with Cytokeratin 19 Antibody (B-1) (see ordering information below).
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SEE ALSO...
Cytokeratin 19 Antibody (B-1) is a mouse monoclonal IgG2b kappa light chain antibody designed to detect Cytokeratin 19, also known as KRT19, a vital intermediate filament protein in epithelial cells. Cytokeratin 19 plays a fundamental role in maintaining the structural integrity and mechanical resilience of epithelial tissues, which is essential for tissue differentiation and specialization. Located within the cytoskeletal network of the cell, Cytokeratin 19 contributes to the formation of intermediate filaments that support cell shape and facilitate intracellular transport, making its cellular localization crucial for its function. Structurally, Cytokeratin 19 consists of a conserved alpha-helical rod domain that enables the polymerization of filaments, providing both stability and flexibility to the cellular architecture. Anti-Cytokeratin 19 antibody (B-1) targets a specific epitope between amino acids 7-29 at the N-terminus of Cytokeratin 19, ensuring reliable detection across multiple species including mouse, rat, human, equine, and porcine. Cytokeratin 19 is widely utilized as a biomarker in cancer research, aiding in the diagnosis and characterization of various malignancies such as breast, liver, and lung cancers due to its expression in tumor cells. Cytokeratin 19 monoclonal antibody (B-1) is compatible with a range of applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA), making it a versatile tool for both research and diagnostic purposes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cytokeratin 19 Antibody (B-1) | sc-374192 | 200 µg/ml | $316.00 | |||
Cytokeratin 19 Antibody (B-1): m-IgG Fc BP-HRP Bundle | sc-537932 | 200 µg Ab; 10 µg BP | $354.00 | |||
Cytokeratin 19 Antibody (B-1): m-IgGκ BP-HRP Bundle | sc-535412 | 200 µg Ab; 40 µg BP | $354.00 | |||
Cytokeratin 19 (B-1) Neutralizing Peptide | sc-374192 P | 100 µg/0.5 ml | $68.00 |