CYTIP Antibody (B-3): sc-514829
- CYTIP Antibody (B-3) is a mouse monoclonal IgG2a κ CYTIP antibody provided at 200 µg/ml
- raised against amino acids 193-344 mapping near the C-terminus of CYTIP of human origin
- CYTIP Antibody (B-3) is recommended for detection of CYTIP of human origin by WB, IP, IF and ELISA
- Anti-CYTIP Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CYTIP Antibody (B-3) for WB applications. These reagents are now offered in bundles with CYTIP Antibody (B-3) (see ordering information below).
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SEE ALSO...
CYTIP Antibody (B-3) is a mouse monoclonal IgG2a kappa light chain antibody that detects CYTIP protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-CYTIP antibody (B-3) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CYTIP, also known as PSCDBP (pleckstrin homology, Sec7 and coiled-coil domains, binding protein), CASP, or CYBR, is primarily located in the cytoplasm and plays a crucial role in lymphocytic cell adhesion. CYTIP′s ability to regulate cytohesin-1, an integrin-activating protein, is vital for maintaining proper cell adhesion and signaling pathways. By mediating the recruitment of cytohesin-1 to the leukocyte membrane, CYTIP prevents its translocation to lymphocytes, effectively interrupting the flow of information in the cell adhesion pathway. CYTIP′s interaction with cytohesin-1 occurs through a PDZ domain, allowing for dynamic localization changes in response to cellular signals. CYTIP can be translocated to the membrane by leukocyte integrins and subsequently relocated to the cytoplasm upon exposure to phorbol esters. CYTIP′s association with sorting nexin 27 (SNX27) underscores a role in coordinating trafficking and signaling complexes, while up-regulation in maturing dendritic cells suggests a significant function in developmentally-controlled cell adhesion.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CYTIP Antibody (B-3) | sc-514829 | 200 µg/ml | $322.00 | |||
CYTIP Antibody (B-3): m-IgG Fc BP-HRP Bundle | sc-531229 | 200 µg Ab; 10 µg BP | $361.00 | |||
CYTIP Antibody (B-3): m-IgGκ BP-HRP Bundle | sc-524857 | 200 µg Ab, 40 µg BP | $361.00 | |||
CYTIP Antibody (B-3): m-IgG2a BP-HRP Bundle | sc-547734 | 200 µg Ab; 10 µg BP | $361.00 | |||
CYTIP Antibody (B-3) AC | sc-514829 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CYTIP Antibody (B-3) HRP | sc-514829 HRP | 200 µg/ml | $322.00 | |||
CYTIP Antibody (B-3) FITC | sc-514829 FITC | 200 µg/ml | $336.00 | |||
CYTIP Antibody (B-3) PE | sc-514829 PE | 200 µg/ml | $349.00 | |||
CYTIP Antibody (B-3) Alexa Fluor® 488 | sc-514829 AF488 | 200 µg/ml | $364.00 | |||
CYTIP Antibody (B-3) Alexa Fluor® 546 | sc-514829 AF546 | 200 µg/ml | $364.00 | |||
CYTIP Antibody (B-3) Alexa Fluor® 594 | sc-514829 AF594 | 200 µg/ml | $364.00 | |||
CYTIP Antibody (B-3) Alexa Fluor® 647 | sc-514829 AF647 | 200 µg/ml | $364.00 | |||
CYTIP Antibody (B-3) Alexa Fluor® 680 | sc-514829 AF680 | 200 µg/ml | $364.00 | |||
CYTIP Antibody (B-3) Alexa Fluor® 790 | sc-514829 AF790 | 200 µg/ml | $364.00 |