cystatin A Antibody (WR23/2/3): sc-32803

Cystatin A Antibody (WR23/2/3) is a mouse monoclonal IgG1 antibody that detects cystatin A in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Cystatin A, also known as STF1, STFA, stefin A, or cystatin AS, is a crucial thiol protease inhibitor that plays a significant role in regulating proteolytic activity within cells. Anti-cystatin A antibody (WR23/2/3) targets a protein primarily located in the cytoplasm and is one of the precursor proteins essential for the formation of the cornified cell envelope in keratinocytes, which is vital for epidermal development and maintenance. Proper functioning of cystatin A helps prevent excessive proteolysis, thereby contributing to skin barrier integrity and protection against environmental stressors. Additionally, cystatin A′s interaction with various proteases, including papain and cathepsins B, H, and L, underscores its role in cellular homeostasis and potential implications in skin-related disorders. Cystatin A monoclonal antibody (WR23/2/3) is an invaluable tool for researchers studying the dynamics of protease inhibition and molecular mechanisms underlying epidermal health.

The preferred cystatin A antibody is cystatin A Antibody (B-11): sc-376759.