Anti-cyclin D3 Antibody (D-7) is a mouse monoclonal IgG1 κ cyclin D3 antibody, cited in 92 publications, provided at 200 µg/ml
raised against amino acids 1-292 representing full length cyclin D3 of human origin
Anti-cyclin D3 Antibody (D-7) is recommended for detection of cyclin D3 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-cyclin D3 Antibody (D-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to TRITC for IF, IHC(P) and FCM
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of cyclin D3 (D-7): sc-6283.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for cyclin D3 Antibody (D-7) for WB and IHC(P) applications. These reagents are now offered in bundles with cyclin D3 Antibody (D-7) (see ordering information below).
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
cyclin D3 Antibody (D-7) is a high quality monoclonal cyclin D3 antibody (also designated CCND3 antibody) suitable for the detection of the cyclin D3 protein of mouse, rat and human origin. cyclin D3 Antibody (D-7) is available as both the non-conjugated anti-cyclin D3 antibody form, as well as multiple conjugated forms of anti-cyclin D3 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The proliferation of eukaryotic cells is controlled at specific points in the cell cycle, particularly at the G1 to S and the G2 to M transitions. It is well established that the Cdc2 p34-cyclin B protein kinase plays a critical role in the G2 to M transition while cyclin A associates with Cdk2 p33 and functions in S phase. Considerable effort directed towards the identification of G1 cyclins has led to the isolation of cyclin D, cyclin C and cyclin. Of these, cyclin D corresponds to a putative human oncogene, designated PRAD1, which maps at the site of the Bcl-1 rearrangement in certain lymphomas and leukemias. Two additional human type D cyclins, as well as their mouse homologs, have been identified. Evidence has established that members of the cyclin D family function to regulate phosphorylation of the retinoblastoma gene product, thereby activating E2F transcription factors.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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