Date published: 2025-10-23

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cyclin D3 Inhibitors

Cyclin D3 inhibitors belong to a specific chemical class of compounds meticulously designed to modulate the activity of cyclin D3, a protein involved in cell cycle regulation and progression. Cyclin D3 plays a crucial role in the G1 phase of the cell cycle by forming complexes with cyclin-dependent kinases (CDKs), facilitating the transition from G1 to S phase. These inhibitors are thoughtfully crafted molecules engineered to interact with cyclin D3, influencing its normal function. Through these interactions, they might impact various cellular processes associated with cell cycle control, cell proliferation, and cellular responses, without directly altering its binding sites or its involvement in CDK complex formation. The design of cyclin D3 inhibitors is grounded in a comprehensive understanding of the structural and functional attributes of cyclin D3. Typically developed using advanced chemical synthesis methods and informed by insights from cell cycle biology and molecular interactions, these inhibitors are characterized by their ability to selectively bind to cyclin D3. This selectivity enables focused modulation of cellular pathways that rely on the activity of cyclin D3 and its interaction with CDKs. Unraveling the intricacies of cell cycle progression, cell proliferation, and molecular interactions often employ cyclin D3 inhibitors as valuable tools. The development and utilization of cyclin D3 inhibitors contribute to advancing our knowledge of the complex interplay between cell cycle components and molecular dynamics, offering insights into the fundamental molecular mechanisms that govern cell cycle progression and contribute to cellular responses to changes in cyclin D3 activity.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Palbociclib

571190-30-2sc-507366
50 mg
$315.00
(0)

This is a well-known CDK4/6 inhibitor that can indirectly inhibit cyclin D3 activity by blocking CDK4 and CDK6, which are required for cyclin D3 to exert its cell cycle-promoting effects.

Ribociclib

1211441-98-3sc-507367
10 mg
$450.00
(0)

Similar to Palbociclib, Ribociclib is another CDK4/6 inhibitor that indirectly affects cyclin D3 function by inhibiting the CDKs with which cyclin D3 forms complexes.

Abemaciclib

1231929-97-7sc-507342
10 mg
$110.00
(0)

Abemaciclib is a CDK4/6 inhibitor as well, and it can have an impact on cyclin D3 by targeting the associated CDKs.

SNS-032

345627-80-7sc-364621
sc-364621A
5 mg
10 mg
$169.00
$262.00
(1)

SNS-032 is a selective inhibitor of CDKs, including CDK2 and CDK7, which can indirectly affect cyclin D3-mediated cell cycle progression.

AT7519

844442-38-2sc-364416
sc-364416A
sc-364416B
sc-364416C
5 mg
10 mg
100 mg
1 g
$207.00
$246.00
$1025.00
$3065.00
1
(0)

AT7519 is a multi-CDK inhibitor with the potential to affect cyclin D3-CDK4/6 complexes.

Dinaciclib

779353-01-4sc-364483
sc-364483A
5 mg
25 mg
$242.00
$871.00
1
(0)

Dinaciclib is a CDK inhibitor that can target CDK1, CDK2, CDK5, and CDK9, which could indirectly influence cyclin D3 interactions.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

Flavopiridol is a CDK9 inhibitor, but it can have broader effects on other CDKs, including those that interact with cyclin D3.

PHA-793887

718630-59-2sc-364580
sc-364580A
5 mg
10 mg
$189.00
$432.00
(0)

This compound is a CDK inhibitor that can impact various CDKs, including those related to cyclin D3 signaling.