cyclin A Antibody (AT10.2): sc-53227
- cyclin A Antibody (AT10.2) is a mouse monoclonal IgG1 κ, cited in 10 publications, provided at 200 µg/ml
- raised against human recombinant cyclin A
- recommended for detection of cyclin A of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See cyclin A (B-8): sc-271682 for cyclin A antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for cyclin A Antibody (AT10.2) for WB and IHC(P) applications. This reagent is now offered in a bundle with cyclin A Antibody (AT10.2) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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Cyclin A Antibody (AT10.2) is a mouse monoclonal IgG1 antibody that detects cyclin A in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-cyclin A antibody (AT10.2) plays a pivotal role in studying the regulation of the eukaryotic cell cycle, particularly during the S phase, where cyclin A is crucial for the proper progression and timing of DNA replication. Cyclin A is primarily located in the nucleus, where cyclin A associates with cyclin-dependent kinase-2 (Cdk2) to form active complexes that drive the cell cycle forward. Precise regulation of cyclin A is vital, as dysregulation can lead to uncontrolled cell proliferation and has been implicated in various cancers. Cyclin A interacts with several key proteins, including the retinoblastoma protein and transcription factors such as E2F, which are essential for cell cycle control and gene expression. Cyclin A monoclonal antibody (AT10.2) is an invaluable tool for researchers studying cell cycle dynamics and the molecular mechanisms underlying cell proliferation and transformation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cyclin A Antibody (AT10.2) | sc-53227 | 200 µg/ml | $322.00 | |||
cyclin A Antibody (AT10.2): m-IgGκ BP-HRP Bundle | sc-551069 | 200 µg Ab; 40 µg BP | $361.00 |