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CWC22 Antibody (A-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects CWC22 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CWC22 (A-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CWC22, also known as NCM, fSAPb, or EIF4GL, is a crucial component of the spliceosome C complex, which plays a vital role in the splicing of pre-mRNA—a key process in post-transcriptional regulation of gene expression. This 908 amino acid nuclear protein is associated with the spliceosome prior to catalytic steps and remains bound throughout the splicing reaction, ensuring accurate removal of introns and joining of exons. The presence of one MI domain and a MIF4G domain in CWC22 is significant, as these domains are essential for interaction with other spliceosomal components, facilitating assembly and function of the spliceosome. The gene encoding CWC22 is located on human chromosome 2q31.3, which is notable for being the second largest human chromosome, comprising approximately 8% of the human genome and containing over 1,400 genes. This extensive genetic landscape underscores the importance of CWC22 in the broader context of gene regulation and cellular function.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CWC22 Antibody (A-6) | sc-398178 | 200 µg/ml | $316.00 | |||
CWC22 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-530714 | 200 µg Ab; 10 µg BP | $354.00 | |||
CWC22 Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-524243 | 200 µg Ab, 40 µg BP | $354.00 | |||
CWC22 Antibody (A-6): m-IgG1 BP-HRP Bundle | sc-544214 | 200 µg Ab; 20 µg BP | $354.00 | |||
CWC22 Antibody (A-6) AC | sc-398178 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CWC22 Antibody (A-6) HRP | sc-398178 HRP | 200 µg/ml | $316.00 | |||
CWC22 Antibody (A-6) FITC | sc-398178 FITC | 200 µg/ml | $330.00 | |||
CWC22 Antibody (A-6) PE | sc-398178 PE | 200 µg/ml | $343.00 | |||
CWC22 Antibody (A-6) Alexa Fluor® 488 | sc-398178 AF488 | 200 µg/ml | $357.00 | |||
CWC22 Antibody (A-6) Alexa Fluor® 546 | sc-398178 AF546 | 200 µg/ml | $357.00 | |||
CWC22 Antibody (A-6) Alexa Fluor® 594 | sc-398178 AF594 | 200 µg/ml | $357.00 | |||
CWC22 Antibody (A-6) Alexa Fluor® 647 | sc-398178 AF647 | 200 µg/ml | $357.00 | |||
CWC22 Antibody (A-6) Alexa Fluor® 680 | sc-398178 AF680 | 200 µg/ml | $357.00 | |||
CWC22 Antibody (A-6) Alexa Fluor® 790 | sc-398178 AF790 | 200 µg/ml | $357.00 |