CTRB1/2 Antibody (D-5): sc-393414
- CTRB1/2 Antibody (D-5) is a mouse monoclonal mouse IgG1 κ κ, cited in 2 publications, provided at 200 µg/ml
- raised against amino acids 76-123 mapping within an internal region of CTRB1 of human origin
- recommended for detection of Chymotrypsinogen B1 of mouse, rat and human origin, and Chymotrypsinogen B2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CTRB1/2 Antibody (D-5) for WB applications. These reagents are now offered in bundles with CTRB1/2 Antibody (D-5) (see ordering information below).
CTRB1/2 Antibody (D-5) is a mouse monoclonal IgG1 antibody that detects Chymotrypsin B (CTRB1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CTRB1/2 antibody (D-5) plays a crucial role in studying the function of chymotrypsins, which are essential digestive enzymes responsible for proteolysis, specifically cleaving peptide bonds at the carboxyl side of aromatic amino acids like tyrosine, tryptophan, and phenylalanine. Understanding the function of CTRB1 is vital, as CTRB1 not only aids in protein digestion but also has implications in various physiological processes, including nutrient absorption and immune response modulation. CTRB1 is synthesized in the pancreas as an inactive precursor, Chymotrypsinogen B1, which is activated through proteolytic cleavage to form a three-polypeptide structure stabilized by disulfide bonds. This activation process is critical, as such regulation ensures enzyme activity only when needed, preventing premature proteolysis that could damage pancreatic tissue. CTRB1/2 (D-5) monoclonal antibody serves as an invaluable tool for researchers investigating the dynamics of chymotrypsin activity and its role in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CTRB1/2 Antibody (D-5) | sc-393414 | 200 µg/ml | $322.00 | |||
CTRB1/2 Antibody (D-5): m-IgG Fc BP-HRP Bundle | sc-538210 | 200 µg Ab; 10 µg BP | $361.00 | |||
CTRB1/2 Antibody (D-5): m-IgGκ BP-HRP Bundle | sc-535778 | 200 µg Ab; 40 µg BP | $361.00 | |||
CTRB1/2 Antibody (D-5): m-IgG1 BP-HRP Bundle | sc-545580 | 200 µg Ab; 20 µg BP | $361.00 |