CSN6 Antibody (D-7): sc-137153
- CSN6 Antibody (D-7) is a mouse monoclonal IgG2a κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 231-268 near the C-terminus of CSN6 of human origin
- recommended for detection of CSN6 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for CSN6 Antibody (D-7) for WB applications. These reagents are now offered in bundles with CSN6 Antibody (D-7) (see ordering information below).
QUICK LINKS
CSN6 Antibody (D-7) is a mouse monoclonal IgG2a antibody that detects CSN6 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CSN6 is a crucial component of the COP9 signalosome complex, which plays a significant role in regulating various developmental and cellular processes. CSN6 is primarily located in the cytoplasm and nucleus, where CSN6 participates in the deneddylation of cullin-RING ligase complexes, thereby modulating the ubiquitin-proteasome pathway. CSN6 is vital for maintaining cellular homeostasis, as CSN6 influences the degradation of key regulatory proteins, including p53 and c-Jun, which are essential for cell cycle control and apoptosis. Dysregulation of CSN6 has been implicated in various diseases, including cancer, making CSN6 an important target for research. Anti-CSN6 antibody (D-7) provides a reliable tool for studying the dynamics of the COP9 signalosome and its impact on cellular signaling pathways, enabling researchers to explore CSN6′s potential as a therapeutic target.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CSN6 Antibody (D-7) | sc-137153 | 200 µg/ml | $322.00 | |||
CSN6 Antibody (D-7): m-IgG Fc BP-HRP Bundle | sc-539949 | 200 µg Ab; 10 µg BP | $361.00 | |||
CSN6 Antibody (D-7): m-IgG2a BP-HRP Bundle | sc-546824 | 200 µg Ab; 10 µg BP | $361.00 | |||
CSN6 (D-7) Neutralizing Peptide | sc-137153 P | 100 µg/0.5 ml | $69.00 |