CSN6 inhibitors form a distinct and intriguing class within the realm of chemical compounds that have garnered considerable attention in molecular and biochemical investigations. These inhibitors are meticulously fashioned to selectively target and engage with the CSN6 protein, a pivotal constituent of the COP9 signalosome complex. The CSN6 protein itself assumes a role of paramount importance in the orchestration of a plethora of fundamental cellular processes. These encompass, but are by no means confined to, the regulation of protein degradation pathways, orchestration of DNA repair mechanisms, meticulous control of cell cycle progression, and intricate modulation of gene expression profiles.
What renders CSN6 inhibitors particularly captivating to researchers is their potential to wield influence over these multifaceted cellular processes. By hampering the enzymatic activity of CSN6, these inhibitors possess the capacity to precipitate far-reaching alterations within cellular pathways. This, in turn, could unveil hitherto concealed facets of the intricate machinery governing cellular functions. They contribute invaluable insights to the broader landscape of cellular signaling cascades, intricate protein-protein interactions, and the convoluted tapestry of molecular occurrences transpiring within cells.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
ZLJ-6 | 1051931-39-5 | sc-224468 sc-224468A | 1 mg 5 mg | $40.00 $180.00 | ||
This small molecule compound was reported to inhibit CSN6 and exhibit anti-cancer effects by affecting cell proliferation and apoptosis. | ||||||
Embelin | 550-24-3 | sc-201555 sc-201555A | 10 mg 50 mg | $89.00 $339.00 | 5 | |
Found in the Embelia ribes plant, embelin has shown potential as a CSN6 inhibitor and has been investigated for its anti-inflammatory and anti-tumor properties. | ||||||
MLN 4924 | 905579-51-3 | sc-484814 | 1 mg | $286.00 | 1 | |
MLN4924 is a well-known CSN6 inhibitor that blocks the activity of the COP9 signalosome complex. It has been explored as an anticancer therapy in research and clinical studies. | ||||||