CRMP-5 Antibody (H-9): sc-376927
- CRMP-5 Antibody (H-9) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 509-534 at the C-terminus of CRMP-5 of human origin
- recommended for detection of CRMP-5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CRMP-5 Antibody (H-9) for WB and IHC(P) applications. These reagents are now offered in bundles with CRMP-5 Antibody (H-9) (see ordering information below).
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CRMP-5 Antibody (H-9) is a mouse monoclonal IgG2b antibody that detects CRMP-5 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CRMP-5, a member of the collapsin response mediator protein family, plays a crucial role in neuronal development and plasticity by mediating signal transduction in response to the axon guidance molecule Semaphorin 3A. CRMP-5 is predominantly located in the filopodia of growth cones during development, which is essential for the proper formation of neural connections. In adult neurons, CRMP-5 continues to be expressed in synapses, highlighting its importance in maintaining synaptic plasticity and facilitating communication between neurons. Notably, CRMP-5 has been implicated in paraneoplastic syndromes, particularly in association with small-cell lung carcinoma and thymoma, where CRMP-5 autoantibodies can serve as a diagnostic marker. Anti-CRMP-5 antibody (H-9) versatility in various applications makes this product an invaluable tool for researchers studying neuronal signaling pathways and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRMP-5 Antibody (H-9) | sc-376927 | 200 µg/ml | $322.00 | |||
CRMP-5 Antibody (H-9): m-IgGκ BP-HRP Bundle | sc-535529 | 200 µg Ab; 40 µg BP | $361.00 | |||
CRMP-5 Antibody (H-9): m-IgG2b BP-HRP Bundle | sc-549444 | 200 µg Ab; 10 µg BP | $361.00 | |||
CRMP-5 (H-9) Neutralizing Peptide | sc-376927 P | 100 µg/0.5 ml | $69.00 |